4.7 Article

Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Urology & Nephrology

Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice

Julie Klein et al.

KIDNEY INTERNATIONAL (2016)

Review Biochemistry & Molecular Biology

Cyclic nucleotide signalling in kidney fibrosis

Elisabeth Schinner et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Article Cell Biology

Cellular Mechanisms of Tissue Fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis

David Lu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2014)

Article Urology & Nephrology

Dose-Dependent Effects of Sirolimus on mTOR Signaling and Polycystic Kidney Disease

Zlata Novalic et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)

Article Physiology

mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease

Franck Belibi et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)

Article Urology & Nephrology

Rapamycin Ameliorates PKD Resulting from Conditional Inactivation of Pkd1

Jonathan M. Shillingford et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)

Article Biochemistry & Molecular Biology

Cyclic AMP Controls mTOR through Regulation of the Dynamic Interaction between Rheb and Phosphodiesterase 4D

Hyun Wook Kim et al.

MOLECULAR AND CELLULAR BIOLOGY (2010)

Article Medicine, General & Internal

Sirolimus and Kidney Growth in Autosomal Dominant Polycystic Kidney Disease

Andreas L. Serra et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Medicine, General & Internal

Everolimus in Patients with Autosomal Dominant Polycystic Kidney Disease

Gerd Walz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Biochemical Research Methods

Comprehensive human urine standards for comparability and standardization in clinical proteome analysis

Harald Mischak et al.

PROTEOMICS CLINICAL APPLICATIONS (2010)

Review Medicine, Research & Experimental

Polycystic Kidney Disease

Peter C. Harris et al.

ANNUAL REVIEW OF MEDICINE (2009)

Article Biochemistry & Molecular Biology

Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis

Cleo S. Bonnet et al.

HUMAN MOLECULAR GENETICS (2009)

Article Biochemistry & Molecular Biology

Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis

Kristen Pollizzi et al.

MOLECULAR CANCER (2009)

Article Multidisciplinary Sciences

Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells

Saskia M. Brachmann et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

Jeffrey A. Engelman et al.

NATURE MEDICINE (2008)

Article Biochemistry & Molecular Biology

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

Klaus Piontek et al.

NATURE MEDICINE (2007)

Article Urology & Nephrology

A functional floxed allele of pkd1 that can be conditionally inactivated in vivo

KB Piontek et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)