相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Bioactive cyclic molecules and drug design
David J. Newman
EXPERT OPINION ON DRUG DISCOVERY (2018)
Current Status of Marine-Derived Compounds as Warheads in Anti-Tumor Drug Candidates
David J. Newman et al.
MARINE DRUGS (2017)
Next-generation sequencing of representational difference analysis products for identification of genes involved in diosgenin biosynthesis in fenugreek (Trigonella foenum-graecum)
Joanna Ciura et al.
PLANTA (2017)
Synthesis and biological evaluation of novel 3-O-tethered triazoles of diosgenin as potent antiproliferative agents
Masood-ur-Rahman et al.
STEROIDS (2017)
(22β,25R)-3β-Hydroxy-spirost-5-en-7-iminoxy-heptanoic acid exhibits anti-prostate cancer activity through caspase pathway
A. A. Hamid et al.
STEROIDS (2017)
Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer
Muthu K. Shanmugam et al.
CURRENT VASCULAR PHARMACOLOGY (2017)
Cancer Statistics, 2017
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2017)
Anticancer potential of Trigonella foenum graecum: Cellular and molecular targets
Khalid El Bairi et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Anti-inflammatory, antioxidant and antiangiogenic activities of diosgenin isolated from traditional medicinal plant, Costus speciosus (Koen ex.Retz.) Sm
Samy Selim et al.
NATURAL PRODUCT RESEARCH (2016)
Natural Products as Sources of New Drugs from 1981 to 2014
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2016)
Antiproliferative, Cytotoxic, and Apoptotic Activity of Steroidal Oximes in Cervicouterine Cell Lines
Luis Sanchez-Sanchez et al.
MOLECULES (2016)
Metastatic colonization by circulating tumour cells
Joan Massague et al.
NATURE (2016)
Developing natural product drugs: Supply problems and how they have been overcome
David J. Newman
PHARMACOLOGY & THERAPEUTICS (2016)
Targeting transcription factor STAT3 for cancer prevention and therapy
Edna Zhi Pei Chai et al.
PHARMACOLOGY & THERAPEUTICS (2016)
Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells
Shanshan Jiang et al.
PHYTOMEDICINE (2016)
Drugs and Drug Candidates from Marine Sources: An Assessment of the Current State of Play
David J. Newman et al.
PLANTA MEDICA (2016)
Bioactive natural products in cancer prevention and therapy: Progress and promise
Anupam Bishayee et al.
SEMINARS IN CANCER BIOLOGY (2016)
Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds
Muthu K. Shanmugam et al.
SEMINARS IN CANCER BIOLOGY (2016)
Design, synthesis of methotrexate-diosgenin conjugates and biological evaluation of their effect on methotrexate transport-resistant cells
Bangrong Cai et al.
STEROIDS (2016)
Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology
Mafalda Jesus et al.
JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY (2016)
A Review on Ethnobotanical and Therapeutic Uses of Fenugreek (Trigonella foenum-graceum L)
Mahmoud Bahmani et al.
JOURNAL OF EVIDENCE-BASED INTEGRATIVE MEDICINE (2016)
Analysis of the intricate relationship between chronic inflammation and cancer
Edna Zhi Pei Chai et al.
BIOCHEMICAL JOURNAL (2015)
Diosgenin-based thio(seleno)ureas and triazolyl glycoconjugates as hybrid drugs. Antioxidant and antiproliferative profile
Laura L. Romero-Hernandez et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
UPLC-QTOF-MS identification of metabolites in rat biosamples after oral administration of Dioscorea saponins: A comparative study
Yi-Na Tang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2015)
Diosgenin Functionalized Iron Oxide Nanoparticles as Novel Nanomaterial Against Breast Cancer
Sougata Ghosh et al.
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2015)
The re-emergence of natural products for drug discovery in the genomics era
Alan L. Harvey et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Broad targeting of angiogenesis for cancer prevention and therapy
Zongwei Wang et al.
SEMINARS IN CANCER BIOLOGY (2015)
Synthetic studies towards 1α-hydroxysolasodine from diosgenin and the unexpected tetrahydrofuran ring opening in the Birch reduction process
Chao Liu et al.
STEROIDS (2015)
How Does Multistep Tumorigenesis Really Proceed?
Christine L. Chaffer et al.
CANCER DISCOVERY (2015)
Advances in the pharmacological activities and mechanisms of diosgenin
Chen Yan et al.
CHINESE JOURNAL OF NATURAL MEDICINES (2015)
Diosgenin inhibits the migration of human breast cancer MDA-MB-231 cells by suppressing Vav2 activity
Zhongmei He et al.
PHYTOMEDICINE (2014)
Novel Medicines and Strategies in Cancer Treatment and Prevention
Chih-Hsin Tang et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Cellular Heterogeneity and Molecular Evolution in Cancer
Vanessa Almendro et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 8 (2013)
A review on pharmacological and analytical aspects of diosmetin: A concise report
Kanika Patel et al.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2013)
Natural Bioactives and Phytochemicals Serve in Cancer Treatment and Prevention
Shun-Fa Yang et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)
Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit
O. Kenny et al.
FOOD CHEMISTRY (2013)
Quantitative Comparison of Multiple Components in Dioscorea nipponica and D. panthaica by Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry
Yina Tang et al.
PHYTOCHEMICAL ANALYSIS (2013)
De Novo Transcriptome Sequencing in Trigonella foenum-graecum L. to Identify Genes Involved in the Biosynthesis of Diosgenin
Kanak Vaidya et al.
PLANT GENOME (2013)
Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer
Muthu K. Shanmugam et al.
CANCER LETTERS (2012)
Anti-Proliferation and Anti-Invasion Effects of Diosgenin on Gastric Cancer BGC-823 Cells with HIF-1α shRNAs
Zhu-Jun Mao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)
Cancer prevention by targeting angiogenesis
Adriana Albini et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2012)
Cancer Cell Signaling Pathways Targeted by Spice-Derived Nutraceuticals
Bokyung Sung et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2012)
Antineoplastic and Apoptotic Potential of Traditional Medicines Thymoquinone and Diosgenin in Squamous Cell Carcinoma
Subhasis Das et al.
PLOS ONE (2012)
Hallmarks of cancer: of all cancer cells, all the time?
Sebastien L. Floor et al.
TRENDS IN MOLECULAR MEDICINE (2012)
Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells
C. Lepage et al.
CANCER LETTERS (2011)
Chemoprevention of Azoxymethane/Dextran Sodium Sulfate-Induced Mouse Colon Carcinogenesis by Freeze-Dried Yam Sanyaku and Its Constituent Diosgenin
Noriyuki Miyoshi et al.
CANCER PREVENTION RESEARCH (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer
Muthu K. Shanmugam et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2011)
Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression
Shern Chen et al.
PLOS ONE (2011)
Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells
Feng Li et al.
CANCER LETTERS (2010)
Epithelial-mesenchymal transition in cancer development and its clinical significance
Masaaki Iwatsuki et al.
CANCER SCIENCE (2010)
Hallmarks of cancer: Interactions with the tumor stroma
Kristian Pietras et al.
EXPERIMENTAL CELL RESEARCH (2010)
The importance of new companies for drug discovery: origins of a decade of new drugs
Robert Kneller
NATURE REVIEWS DRUG DISCOVERY (2010)
Fenugreek A naturally occurring edible spice as an anticancer agent
Shabana Shabbeer et al.
CANCER BIOLOGY & THERAPY (2009)
Impact of Natural Products on Developing New Anti-Cancer Agents
Gordon M. Cragg et al.
CHEMICAL REVIEWS (2009)
Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells
Sowmyalakshmi Srinivasan et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
A review of high throughput technology for the screening of natural products
K. P. Mishra et al.
BIOMEDICINE & PHARMACOTHERAPY (2008)
Natural products as leads to potential drugs: An old process or the new hope for drug discovery?
David J. Newman
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Targeting nuclear factor-κB activation pathway by thymoquinone:: Role in suppression of antiapoptotic gene products and enhancement of apoptosis (Publication with Expression of Concern. See vol. 16, pg. 1441, 2018)
Gautam Sethi et al.
MOLECULAR CANCER RESEARCH (2008)
Potential of Spice-Derived Phytochemicals for Cancer Prevention
Bharat B. Aggarwal et al.
PLANTA MEDICA (2008)
Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation
Chun-Te Chiang et al.
FEBS LETTERS (2007)
Back to basics: how natural products can provide the basis for new therapeutics
Amit Deorukhkar et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2007)
Nuclear factor-kappa B: From clone to clinic
Kwang Seok Ahn et al.
CURRENT MOLECULAR MEDICINE (2007)
Opinion - Angiogenesis: an organizing principle for drug discovery?
Judah Folkman
NATURE REVIEWS DRUG DISCOVERY (2007)
Fenugreek (Trigonella foenum-graecum):: A review of health beneficial physiological effects
K Srinivasan
FOOD REVIEWS INTERNATIONAL (2006)
Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, IκB kinase activation and NF-κB-regulated gene expression
S Shishodia et al.
ONCOGENE (2006)
Diosgenin-3-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranoside obtained as a new anticancer agent from Dioscorea futschauensis induces apoptosis on human colon carcinoma HCT-15 cells via mitochondria-controlled apoptotic pathway
SL Wang et al.
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2004)
Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells
C Corbiere et al.
CELL RESEARCH (2004)
Natural product hybrids as new leads for drug discovery
LF Tietze et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Role of angiogenesis in tumor growth and metastasis
J Folkman
SEMINARS IN ONCOLOGY (2002)
A plant steroid, diosgenin, induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells
S Moalic et al.
FEBS LETTERS (2001)
分享论文
