期刊
NUTRIENTS
卷 10, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/nu10030313
关键词
dietary patterns; dietary variety; mortality; dietary guidelines; public health
资金
- Swiss National Science Foundation (National Research Program 69 Healthy and sustainable diets) [406940-166764]
- Swiss National Science Foundation [3347CO-108806, 33CS30_134273, 33CS30_148415]
- Swiss Federal Statistical Office
- Swiss National Science Foundation (SNF) [406940_166764] Funding Source: Swiss National Science Foundation (SNF)
Defining dietary guidelines requires a quantitative assessment of the influence of diet on the development of diseases. The aim of the study was to investigate how dietary patterns were associated with mortality in a general population sample of Switzerland. We included 15,936 participants from two population-based studies (National Research Program 1A (NRP1A) and Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA)-1977 to 1993) who fully answered a simplified 24-h dietary recall. Mortality data were available through anonymous record linkage with the Swiss National Cohort (follow-up of up to 37.9 years). Multiple correspondence analysis and hierarchical clustering were used to define data-driven qualitative dietary patterns. Mortality hazard ratios were calculated for all-cause, cancer and cardiovascular mortality using Cox regression. Two patterns were characterized by a low dietary variety (Sausage and Vegetables, Meat and Salad), two by a higher variety (Traditional, High-fiber foods) and one by a high fish intake (Fish). Males with unhealthy lifestyle (smokers, low physical activity and high alcohol intake) were overrepresented in the low-variety patterns and underrepresented in the high-variety and Fish patterns. In multivariable-adjusted models, the Fish (hazard ratio = 0.82, 95% CI (0.68-0.99)) and High-fiber foods (0.85 (0.72-1.00)) patterns were associated with lower cancer mortality. In men, the Fish (0.73 (0.55-0.97)) and Traditional (0.76 (0.59-0.98)) patterns were associated with lower cardiovascular mortality. In summary, our results support the notion that dietary patterns affect mortality and that these patterns strongly cluster with other health determinants.
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