期刊
BIOMEDICAL OPTICS EXPRESS
卷 9, 期 2, 页码 616-622出版社
Optica Publishing Group
DOI: 10.1364/BOE.9.000616
关键词
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资金
- National Institutes of Health (NIH) [R01 CA167421, R01 CA210544]
- National Science Foundation (NSF) [CBET 1604562]
- NVIDIA Corporation
Speckle is an intrinsic noise of interferometric signals which reduces contrast and degrades the quality of optical coherence tomography (OCT) images. Here, we present a frequency compounding speckle reduction technique using the dual window (DW) method. Using the DW method, speckle noise is reduced without the need to acquire multiple frames. A -25% improvement in the contrast-to-noise ratio (CNR) was achieved using the DW speckle reduction method with only minimal loss (-17%) in axial resolution. We also demonstrate that real-time speckle reduction can be achieved at a B-scan rate of -21 frames per second using a graphic processing unit (GPU). The DW speckle reduction technique can work on any existing OCT instrument without further system modification or extra components. This makes it applicable both in real-time imaging systems and during post-processing. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
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