期刊
NATURE COMMUNICATIONS
卷 9, 期 -, 页码 -出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41467-018-04510-3
关键词
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资金
- Research Grants Council of Hong Kong [HKU 707712P, HKU 719813E, 17304514, 17306315, C6004-14G]
- National Natural Science Foundation of China [91434202, 21476189/B060201]
- National Science Foundation of USA [IIP1456281]
- Swiss National Science Foundation
- Peterhouse Cambridge
- European Research Council under the European Union [337969]
- Wellcome Trust
- Frances and Augustus Newman Foundation
Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that artificial networks of protein nanofibrils can induce controlled deformation and division of all-aqueous emulsion droplets with budding-like morphologies. We show that this process is driven by the difference in the immersional wetting energy of the nanofibril network, and that both the size and the number of the daughter droplets formed during division can be controlled by modulating the fibril concentration and the chemical properties of the fibril network. Our results demonstrate a route for achieving biomimetic division with synthetic self-assembling fibrils and offer an engineered approach to regulate the morphology of protein gels.
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