相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Opening of the human epithelial calcium channel TRPV6
Luke L. McGoldrick et al.
NATURE (2018)
Identification and characterization of hydrophobic gate residues in TRP channels
Wang Zheng et al.
FASEB JOURNAL (2018)
Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2
Wang Zheng et al.
CELL REPORTS (2018)
Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium
Xiaowen Liu et al.
ELIFE (2018)
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2)
Mariana Grieben et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2)
Mariana Grieben et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Electron cryo-microscopy structure of the mechanotransduction channel NOMPC
Peng Jin et al.
NATURE (2017)
Human TRPML1 channel structures in open and closed conformations
Philip Schmiege et al.
NATURE (2017)
Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3
Marscha Hirschi et al.
NATURE (2017)
Structure of mammalian endolysosomal TRPML1 channel in nanodiscs
Qingfeng Chen et al.
NATURE (2017)
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
Shawn Q. Zheng et al.
NATURE METHODS (2017)
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2
Martin Wilkes et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2
Martin Wilkes et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
The S4-S5 linker - gearbox of TRP channel gating
Laura Hofmann et al.
CELL CALCIUM (2017)
The native TRPP2-dependent channel of murine renal primary cilia
Steven J. Kleene et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2017)
The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs
Peter S. Shen et al.
CELL (2016)
Effect of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease by CKD Stage: Results from the TEMPO 3:4 Trial
Vicente E. Torres et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
Regulation of TRPP3 Channel Function by N-terminal Domain Palmitoylation and Phosphorylation
Wang Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Primary cilia are not calcium-responsive mechanosensors
M. Delling et al.
NATURE (2016)
Crystal structure of the epithelial calcium channel TRPV6
Kei Saotome et al.
NATURE (2016)
The polycystin complex mediates Wnt/Ca2+ signalling
Seokho Kim et al.
NATURE CELL BIOLOGY (2016)
Cryo-electron microscopy structure of the TRPV2 ion channel
Lejla Zubcevic et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant
Mahmud Arif Pavel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Cryo-electron microscopy structure of the TRPV2 ion channel
Lejla Zubcevic et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Atypical calcium regulation of the PKD2-L1 polycystin ion channel
Paul G. DeCaen et al.
ELIFE (2016)
Hydrophobic Gating in Ion Channels
Prafulla Aryal et al.
JOURNAL OF MOLECULAR BIOLOGY (2015)
Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage
Xueming Li et al.
JOURNAL OF STRUCTURAL BIOLOGY (2015)
CTFFIND4: Fast and accurate defocus estimation from electron micrographs
Alexis Rohou et al.
JOURNAL OF STRUCTURAL BIOLOGY (2015)
A polycystin-centric view of cyst formation and disease: the polycystins revisited
Albert C. M. Ong et al.
KIDNEY INTERNATIONAL (2015)
Structure of the TRPA1 ion channel suggests regulatory mechanisms
Candice E. Paulsen et al.
NATURE (2015)
Genetic compensation induced by deleterious mutations but not gene knockdowns
Andrea Rossi et al.
NATURE (2015)
Acid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca2+
Shaimaa Hussein et al.
SCIENTIFIC REPORTS (2015)
The number and location of EF hand motifs dictates the calcium dependence of polycystin-2 function
Ivana Y. Kuo et al.
FASEB JOURNAL (2014)
TRPV1 structures in distinct conformations reveal activation mechanisms
Erhu Cao et al.
NATURE (2013)
Direct recording and molecular identification of the calcium channel of primary cilia
Paul G. DeCaen et al.
NATURE (2013)
Primary cilia are specialized calcium signalling organelles
Markus Delling et al.
NATURE (2013)
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
Maofu Liao et al.
NATURE (2013)
Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease
Ming Ma et al.
NATURE GENETICS (2013)
Receptor for Activated C Kinase 1 (RACK1) Inhibits Function of Transient Receptor Potential (TRP)-type Channel Pkd2L1 through Physical Interaction
Jungwoo Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Calcium-induced Conformational Changes in C-terminal Tail of Polycystin-2 Are Necessary for Channel Gating
Andjelka S. Celic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
Sjors H. W. Scheres
JOURNAL OF STRUCTURAL BIOLOGY (2012)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
Primary cilia regulate mTORC1 activity and cell size through Lkb1
Christopher Boehlke et al.
NATURE CELL BIOLOGY (2010)
Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity
Edward T. Petri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The gates of ion channels and enzymes
Huan-Xiang Zhou et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
Polycystic Kidney Disease
Peter C. Harris et al.
ANNUAL REVIEW OF MEDICINE (2009)
Regulation of the murine TRPP3 channel by voltage, pH, and changes in cell volume
Takahiro Shimizu et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2009)
Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1
Surya M. Nauli et al.
CIRCULATION (2008)
Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis
Andjelka Celic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The structure of an open form of an E. coli mechanosensitive channel at 3.45 Å resolution
Wenjian Wang et al.
SCIENCE (2008)
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella
Kaiyao Huang et al.
JOURNAL OF CELL BIOLOGY (2007)
Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling
Chang Xu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor
Yoshiro Ishimaru et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Two different conformational states of the KirBac3.1 potassium channel revealed by electron crystallography
AL Kuo et al.
STRUCTURE (2005)
Organic cation permeation through the channel formed by polycystin-2
GI Anyatonwu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney
ZX Sun et al.
DEVELOPMENT (2004)
Regulation of calcium signaling by polycystin-2
HF Cantiello
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812
YQ Cai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Crystal structure of the potassium channel KirBac1.1 in the closed state
AL Kuo et al.
SCIENCE (2003)
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
SM Nauli et al.
NATURE GENETICS (2003)
The open pore conformation of potassium channels
YX Jiang et al.
NATURE (2002)
Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations
T Watnick et al.
NATURE GENETICS (2000)