期刊
JOURNAL OF FUNCTIONAL FOODS
卷 43, 期 -, 页码 8-16出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jff.2018.01.025
关键词
Sargassum fusiforme; Polysaccharides; Ultraviolet B; Oxidative stress; Skin protection
资金
- Guangdong Special Support Program [2015TQ01N670]
- Pearl River S&T Nova Program of Guangzhou [201610010096]
- Fundamental Research Funds for the Central Universities [2015ZZ110]
- Group Program of Natural Science Foundation of Guangdong Province [2016A030312001]
Sargassum fusiforme polysaccharide (SFP) was extracted from Sargassum fusiforme by hot water boiling, concentration and ethanol precipitation. The composition was determined as 58.10 +/- 2.12% carbohydrate, 1.01 +/- 0.15% protein, 9.85 +/- 0.96% sulfate group and 17.66 +/- 0.54% glucuronic acid. The average molecular weight of SFP was 224 kDa. The monosaccharide composition of SFP was 43.2% L-fucose, 3.5% rhamnose, 18.4% galactose, 1.5% glucose, 18.5% fructose, 5.9% xylose and 9.0% mannose respectively. SFP showed significant protective effect against ultraviolet B (UVB) radiation in hairless Kun Ming (KM) mice by manipulating the skin water content and thymus and spleen indexes. SFP could also alleviate UVB-induced oxidative stress by enhancing the activities of superoxide dismutase (SOD) and catalase (CAT) and reducing the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) equivalents. The levels of matrix metailoproteinase (MMP)-1 and 9 were also suppressed in SFP treatments. These findings suggest that SFP could be used as a potential functional food supplement for skin protection.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据