期刊
CHEMICAL SCIENCE
卷 9, 期 6, 页码 1424-1432出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7sc04768a
关键词
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资金
- Frasch Foundation
- William Rainey Harper Dissertation Fellowship
- Bristol-Myers Squibb
The application of exo-type directing groups (DGs) has led to the discovery of a wide range of novel C(sp(3))-Hactivation methods, which allow efficient and site-selective functionalization of alcohol and amide derivatives. In this mini-review we discuss the challenges of this field and summarize the achievements, including DG designs, reaction discoveries and mechanistic studies.
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