期刊
CHEMICAL SCIENCE
卷 9, 期 33, 页码 6839-6843出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8sc02101e
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资金
- National Natural Science Foundation of China [21602115]
- 1000-Talent Youth Program [020/BF180181]
- Natural Science Foundation of Tianjin [18JCYBJC20400]
- Fundamental Research Funds for the Central Universities
- Nankai University
Herein, we describe the first linear-selective hydroarylation reaction of unactivated alkenes and styrenes with aryl boronic acids, which was achieved by introducing a directing group on the alkenes. This efficient, scalable reaction serves as a method for modular assembly of structurally diverse alkyl arenes, including -aryl butyric acid derivatives, which are widely utilized as chemical building blocks for the synthesis of various drugs and other biologically active compounds.
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