4.8 Article

Enantioselective cellular localisation of europium(III) coordination complexes

期刊

CHEMICAL SCIENCE
卷 9, 期 4, 页码 1042-1049

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c7sc04422d

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  1. EPSRC
  2. Royal Society
  3. EPSRC [EP/L019124/1, EP/I010319/1, EP/P025013/1] Funding Source: UKRI
  4. Engineering and Physical Sciences Research Council [EP/L019124/1, EP/I010319/1, EP/P025013/1] Funding Source: researchfish

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The selective mitochondrial localisation of the L enantiomer of three different emissive europium(III) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the (sic) enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs via macropinocytosis.

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