Preyssler-Pope-Jeannin Polyanions [NaP5W30O110]14- and [AgP5W30O110]14-: Microwave-Assisted Synthesis, Structure, and Biological Activity

The Preyssler-Pope-Jeannin polyanion [NaP5W30O110](14-) (1) was prepared by microwave-assisted synthesis in only 2 h with a yield comparable to the reported hydrothermal procedure. The purity of 1 was confirmed by FT-IR and multinuclear NMR (P-31, W-183) analysis. The silver(I)-containing analogue [AgP5W30O110](14-) (2) was also prepared by hydrothermal (6 d) as well as microwave-based (2 h) procedures. Polyanion 2 was characterized in the solid state by FT-IR, single-crystal XRD, TGA, and elemental analysis and in solution by P-31 and W-183 NMR, and ESI-MS. The antiproliferative activities against human cells as well as the antimicrobial properties towards Gram-positive and Gram-negative bacteria were comparatively evaluated for 1 and 2.