期刊
YONSEI MEDICAL JOURNAL
卷 59, 期 4, 页码 563-565出版社
YONSEI UNIV COLL MEDICINE
DOI: 10.3349/ymj.2018.59.4.563
关键词
F-18-AV-1451 PET; subacute infarction; tau; blood-brain-barrier
资金
- National Research Foundation of Korea (NRF) - Korea government (MSIP) [NRF-2015R1C1A2A01053281]
- NRF - Korean government (MSIP) [2014M3C7A1064752]
- NRF - Korea government (MSIP) [NRF-2017R1A2B2005081]
- Research of Korea Centers for Disease Control and Prevention [2017-ER6203-00]
- Korea Ministry of Environment (MOE) [1485014533]
- Korea Health Promotion Institute [2017-ER6203-00] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
F-18-AV-1451 is a tau PET ligand that has high affinity for paired helical filament tau. However, various off-target bindings unrelated to tau have also been reported. Herein, we report a case of 83-year-old woman, who showed abnormal uptake of AV-1451 that was shown to be subacute infarction. Clinicians should recognize that increased uptake of AV-1451 may be related to stroke.
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