A new analytical device incorporating a nitrogen doped lanthanum metal oxide with reduced graphene oxide sheets for paracetamol sensing

The novel N-CeO2 nanoparticles decorated on reduced graphene oxide (N-CeO2@rGO) composite has been synthesized by sonochemical method. The characterization of as prepared nanocomposite was intensely performed by UV-Vis, FT-IR, EDX, FE-SEM, HR-TEM, XRD, and TGA analysis. The synthesized nanomaterial was further investigated for its selective and sensitive sensing of paracetamol (PM) based on a N-CeO2@rGO modified glassy carbon electrode. A distinct and improved reversible redox peak of PM is obtained at N-CeO2@rGO nanocomposite compared to the electrodes modified with N-CeO2 and rGO. It displays a very good performance with a wide linear range of 0.05-0.600 mu M, a very low detection limit of 0.0098 mu M (S/N = 3), a high sensitivity of 268 A mu M-1 cm(-2) and short response time (< 3 s). Also, the fabricated sensor shows a good sensibleness for the detection of PM in various tablet samples.