期刊
TRIALS
卷 19, 期 -, 页码 -出版社
BIOMED CENTRAL LTD
DOI: 10.1186/s13063-018-2535-5
关键词
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资金
- UK Network of MRC Hubs for Trials Methodology Research
- Irish Trials Methodology Research Network
- MRC [MR/L004933/1, G1002325, MR/L004933/2, G0901530] Funding Source: UKRI
- Chief Scientist Office [HSRU1] Funding Source: researchfish
- Medical Research Council [G0901530, G1002325, MR/L004933/1, MR/L004933/2] Funding Source: researchfish
Randomised trials are a central component of all evidence-informed health care systems and the evidence coming from them helps to support health care users, health professionals and others to make more informed decisions about treatment. The evidence available to trialists to support decisions on design, conduct and reporting of randomised trials is, however, sparse. Trial Forge is an initiative that aims to increase the evidence base for trial decision-making and in doing so, to improve trial efficiency. One way to fill gaps in evidence is to run Studies Within A Trial, or SWATs. This guidance document provides a brief definition of SWATs, an explanation of why they are important and some practical 'top tips' that come from existing experience of doing SWATs. We hope the guidance will be useful to trialists, methodologists, funders, approvals agencies and others in making clear what a SWAT is, as well as what is involved in doing one.
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