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Panomics for Precision Medicine

期刊

TRENDS IN MOLECULAR MEDICINE
卷 24, 期 1, 页码 85-101

出版社

ELSEVIER SCI LTD
DOI: 10.1016/j.molmed.2017.11.001

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资金

  1. Research Chair from the Ontario College of Universities
  2. NIH [1RO1DK110520-01]
  3. NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK110520] Funding Source: NIH RePORTER

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Medicine is poised to undergo a digital transformation. High-throughput platforms are creating terabytes of genomic, transcriptomic, proteomic, and metabolomic data. The challenge is to interpret these data in a meaningful manner - to uncover relationships that are not readily apparent between molecular profiles and states of health or disease. This will require the development of novel data pipelines and computational tools. The combined analysis of multi-dimensional data is referred to as 'panomics'. The ultimate hope of integrative panomics is that it will lead to the discovery and application of novel markers and targeted therapeutics that drive forward a new era of 'precision medicine' where inter-individual variation is accounted for in the treatment of patients.

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