期刊
TRENDS IN CELL BIOLOGY
卷 28, 期 4, 页码 274-286出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcb.2017.12.001
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资金
- Fonds de la Recherche Scientifique-FNRS
- Fonds de la Recherche Scientifique-FNRS [PDR-T.0206.16]
- Federation Wallonie-Bruxelles (Actions de Recherche Concertees) [17/22-085]
- Agence Nationale pour la Recherche [ANR-14-CE16-0004-03, ANR-14-CE14-0002-02, ANR-16-CE23-0005-02]
- Human Frontier Science Program [RGP0029-2014]
- European Research Council [340485]
- European Union program H-MSCA-ITN BIOPOL
- Swedish Research Council
Membrane fission is essential to life. It is required for many fundamental cellular processes, as diverse as cyto- and karyokinesis, organelle division, membrane repair, and membrane trafficking and endocytosis. While membrane fission was originally seen as resulting from the action of mechanoenzymes such as dynamin, it is clear that the reality is more complex. In this review, we propose an updated overview of fission mechanisms, and try to extract essential requirements for each. We also present examples of cellular processes that involve these fission mechanisms. Finally, we list pending questions, whether they are specific to a peculiar fission mechanism or more general to the field.
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