期刊
THORAX
卷 73, 期 10, 页码 980-982出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/thoraxjnl-2017-210661
关键词
-
资金
- European COST (Cooperation in Science and Technology) [BM1407 BEAT-PCD]
Cilia have multiple functions including olfaction. We hypothesised that olfactory function could he impaired in primary ciliary dyskinesia (PCD). Olfaction, nasal nitric oxide (nNO) and sinus CT were assessed in patients with PCD and non-PCD sinus disease, and healthy controls (no CT scan). PCD and non-PCD patients had similar severity of sinus disease. Despite this, defective olfaction was more common in patients with PCD (P<0.0001) and more severe in patients with PCD with major Transmission Electron Microscopy (TEM) abnormalities. Only in classical PCD did olfaction inversely correlate with sinusitis and nNO. We speculate that defective olfaction in PCD is primary in nature.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据