期刊
TETRAHEDRON
卷 74, 期 9, 页码 975-986出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2018.01.019
关键词
Fluorinated aminophosphonates; Phenylglycine; Homophenylalanine; Amino acids; DFT calculations; X-ray analysis
资金
- PL-Grid Infrastructure
Novel perfluorophenyl phosphonate analogues of phenylglycine and homophenylalanine were prepared in good to excellent yields, and subjected to solid state characterization by single-crystal X-ray diffraction analysis, and to investigations with the use of DFT methods. The alpha-aminophosphonates have a big potential for biological activity, and through SNAr reactions may give an entrance to further structurally variable analogues of both amino acids. (C) 2018 Elsevier Ltd. All rights reserved.
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