期刊
TALANTA
卷 189, 期 -, 页码 254-261出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.talanta.2018.06.075
关键词
Ni-MOF nanosheets; TMB H2O2; Human serum; Colorimetric method
资金
- NSFC [21705141, 21275124, 21275125, 21575124, 21675140]
- Jiangsu Planned Projects for Postdoctoral Research Funds [1601075C]
- Postdoctoral Science Foundation of China [2016M601897]
- PAPD
- TAPP of Jiangsu Higher Education Institutions
- High-end Talent Project of Yangzhou University
- 14th Six talent peaks project in Jiangsu Province [SWYY-085]
- Higher Education Outstanding Scientific and Technological Innovation Team of Jiangsu Province [2017-6]
- Graduate Innovation Project Foundation of Jiangsu province [KYLX 1333, KYLX 1334]
- Natural Science Research Projects of Jiangsu Higher Education [16KJB150044]
- Yangzhou University Innovation and Cultivation Fund [2016CXJ014]
A two-dimensional (2D) Ni based metal-organic framework (MOF) nanosheets were synthesized using a one-step solvent-thermal method. The as-prepared nanosheets were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), powder X-ray diffraction (XRD) and energy disperse spectroscopy (EDS) mapping. Ni-MOF nanosheet was first time found to used as a peroxidase mimetic with catalytic activities and could catalyze the oxidation of the substrate 3,3,5,5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H2O2). Catalytic mechanism analysis suggested the enzymatic kinetics of Ni-MOF nanosheets followed typical Michaelis-Menten theory and Ni-MOF nanosheets possess a higher affinity for two substrates (TMB and H2O2) than horseradish peroxidase (HRP). Furthermore, Ni-MOF nanosheet was applied to establish an H2O2 colorimetric sensor which deserves a wide linear range of 0.04 similar to 60 mu M and a low detection limit of 8 nM. Also the application of this sensor for H2O2 detection in human serum and disinfectant was demonstrated and satisfactory results were obtained. Thus, the simple and sensitive Ni-MOF/TMB/H2O2 colorimetric system has great promising applications in clinical medicine and food environment analysis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据