Synthetic Strategies for the Regioselective Functionalization of Tribenzotriquinacenes

The rigid molecular scaffold of the tribenzotriquinacenes (TBTQs) has emerged as a versatile structural platform that possesses unique geometrical features and allows for an orthogonal arrangement of organic functional substituents or convex-concave interactions. In this review, we summarize and discuss important synthetic strategies for a regioselective functionalization at the four distinct positions of the TBTQ basic framework, namely, apical, bridgehead, ortho, and outer rim.