Organophotoredox/Copper Hybrid Catalysis for Regioselective Allylic Aminodecarboxylation of beta,gamma-Unsaturated Carboxylic Acids

A new cooperative organophotoredox/copper catalysis allowing for the conversion of ,-unsaturated carboxylic acids into allylic hydrazides via radical regioselective allylic decarboxylative amination is reported. The coexistence of the copper catalyst is essential for the high yield and regioselectivity.