期刊
SYNTHESIS-STUTTGART
卷 50, 期 10, 页码 1979-1990出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1591768
关键词
trifluoromethylated; N-acylhydrazones; maleates; pyrazolidines; cycloaddition; trifluoromethyl building blocks
An efficient [3+2] cycloaddition reaction of trifluoromethylated N-acylhydrazones with dimethyl maleate has been developed under basic conditions. This protocol provides an easy access to potentially bioactive trifluoromethylated pyrazolidines in moderate to excellent yields. It also illustrates that the trifluoromethylated N-acylhydrazones are useful trifluoromethyl building blocks for the synthesis of trifluoromethylated N-heterocycles.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据