期刊
SYNTHESIS-STUTTGART
卷 50, 期 12, 页码 2323-2328出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1591989
关键词
thionation; P (4); S; (10); Lawesson's reagent; biologically active compounds; antivirals
Pyridine reacts readily with P (4) S (10) to form a reagent with the composition C (10) H (10) N (2) P (2) S (5) that is useful for thionations of amides. The thionating properties of this reagent are compared with those of Lawesson's reagent. 1 Introduction 2 Development of C (10) H (10) N (2) P (2) S (5) 3 Use of Thionation for Modification of Biologically Active Compounds 3.1 Thionations of Peptides 3.2 Thionated Compounds of Interest as Potential Antivirals 3.3 Thionations of Thalidomide and Related Molecules 4 Comparison of Lawesson's Reagent and C (10) H (10) N (2) P (2) S-5
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