期刊
GLOBAL SPINE JOURNAL
卷 2, 期 4, 页码 239-248出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0032-1315454
关键词
bone graft substitute; spine fusion; biologics; osteobiologics; demineralized bone matrix; ceramics; bone morphogenetic protein; autograft
资金
- Orthopaedic Research and Education Foundation (OREF) [11-278]
Bone graft substitutes have been used routinely for spine fusion for decades, yet clinical evidence establishing comparative data remains sparse. With recent scrutiny paid to the outcomes, complications, and costs associated with osteobiologics, a need to improve available data guiding efficacious use exists. We review the currently available clinical literature, studying the outcomes of various biologics in posterolateral lumbar spine fusion, and establish the need for a multicenter, independent osteobiologics registry.
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