期刊
SOUTH AFRICAN JOURNAL OF BOTANY
卷 120, 期 -, 页码 119-123出版社
ELSEVIER
DOI: 10.1016/j.sajb.2018.01.010
关键词
Antioxidant; Tyrosinase; Phenolic; Flavonoid; Hyperpigmentation; Enzyme inhibitors; Botanical remedies
Traditionally used botanical remedies have attracted much interest as pharmacological targets in the management and/or treatment of several diseases. Recently, they have been probed as tyrosinase inhibitors for the management of epidermal hyperpigmentation. This study aims to investigate into the antioxidant and tyrosinase inhibitory potential of methanol, ethyl acetate, and water extracts of three medicinal plants (Consolida orientalis (J. Gay) Schrodinger, Onosma isauricumBoiss. & Heldr. and Spartium junceumL.), fromTurkey. Methanolic extract of O. isauricum and S. junceum showed the highest phenolic (63.08 mgGAE/g extract) and flavonoid contents (45.55 mgRE/g extract). Additionally, O. isauricum methanolic extract exhibited the most powerful antioxidant capacity followed by methanolic extract of S. junceum (86.02 and 62.81 mgAAE/g extract, respectively). S. junceum extracts yielded the higher kojic acid equivalent values (21.42-23.04 mgKAE/g extract), confirming that these extracts were the most potent inhibitors of tyrosinase. S. junceum showed promising activity that warrant further studies and could be considered as a potent candidate for the development of phytoremedies for the management of epidermal hyperpigmentation. To the best of our knowledge, this study can be considered as the first report of on the antioxidant and tyrosinase inhibitory action of C. orientalis, O. isauricum, and S. junceum from Turkey. (c) 2018 SAAB. Published by Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据