期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 262, 期 -, 页码 892-901出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2018.02.074
关键词
Droplet manipulation; Superhydrophobic magnetic film; Electromagnetic pillar array; Crystallization
资金
- National Natural Science Foundation of China [61771078, 21407016]
- National Key Research and Development Program [2016YFC0101100]
- Chongqing Research Program of Basic Research and Frontier Technology [cstc2017jcyjB0182]
- Fundamental Research Funds for the Central Universities [10611CDJXZ238826]
In this paper, we present a novel magnetic digital microfluidic platform that combines a superhydrophobic magnetic film (SHMF) with an electromagnetic pillar array (EMPA) for droplet manipulation. Upon dynamic excitation of the EMPA under the SHMF, the surface topography of the SHMF was programmatically changed, which can direct and control the motion of aqueous droplets efficiently and accurately by utilizing gravitational force. Using this platform, we demonstrated the following droplet operations: path-programmable transportation of droplets, parallel transportation of multiple droplets, merging and mixing of multiple droplets. In particular, a rapid and efficient mixing was easily achieved by oscillating the coalesced droplets with the frequent switching of magnetic actuation of the EMPA (e.g., by applying AC current). We also demonstrated the applicability of this platform as a new type of open-surface digital microfluidic device using a simple crystallization experiment. We believe that this platform is appealing for biological microanalyses and chemical microreactions because it provides a means for pure droplet manipulation without any additives (e.g., magnetic particles), and allows better scalability and programmability of droplet manipulation. (C) 2018 Elsevier B.V. All rights reserved.
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