Cobalt nitride nanowire array as an efficient electrochemical sensor for glucose and H2O2 detection

It is highly attractive to develop non-noble-metal nanoarray architecture as a high-active catalyst electrode for molecular detection due to its large specific surface area and easy accessibility to target molecules. In this paper, we demonstrate the development of cobalt nitride nanowire array on Ti mesh(Co3N NW/TM) as an efficient catalyst electrode for glucose oxidation in alkaline solutions and H2O2 reduction in neutral solutions. Electrochemical tests suggest that such Co3N NW/TM possesses superior non-enzymatic sensing ability toward rapid glucose and H2O2 detection. As a glucose sensor, this fabricated electrode offers a high sensitivity of 3325.6 mu A mM(-1)cm(- 2), with a wide linear range from 0.1 mu M to 2.5 mM, a low detection limit of 50 nM (S/N = 3), and satisfactory stability and reproducibility. Its application in determining glucose in human blood serum is also successful. Amperometric H2O2 sensing canalso been realized with a sensitivity of 139.9 mu A mM(-1)cm(-2), a linear range from 2 mu M to 28 mM, and adetection limit of 1 mu M (S/N = 3). This nanoarray architecture holds great promise as an attractive sensing platform toward electrochemical small molecules detection. (C) 2017 Published by Elsevier B.V.