A dual sensor selective for Hg2+ and cysteine detection

A new sensor for Hg2+ and cysteine detection has been synthesized and tested. The sensor based on cinamaldehyde and pyrimidine absorbs visible light when exposed to Hg2+ and becomes colored. The sensor only changes color due to Hg2+ and does not change when exposed to some other metal ions. Calculations show the change in color is due to lowering of the HOMO-LUMO transition. Titrations show the sensor-Hg2+ complex is composed of two sensor molecules per Hg2+. The limit of detection for Hg2+ is 0.39 mu M. The sensor-Hg2+ complex selectively responds to cysteine (Cys), but does not show a color change due to other amino acids. The limit of detection of Cys by the sensor-Hg2+ complex is 0.10 mu M. (C) 2017 Elsevier B.V. All rights reserved.