期刊
SENSORS
卷 18, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/s18040942
关键词
POC testing devices; kidney disease; chemical sensors; biosensors
资金
- Australian Research Council [DP150101939, DE160100569]
- Westpac2016 Research Fellowship
- University of Messina under the scheme of RM program
This review reports the latest achievements in point-of-care (POC) sensor technologies for the monitoring of ammonia, creatinine and urea in patients suffering of chronic kidney diseases (CKDs). Abnormal levels of these nitrogen biomarkers are found in the physiological fluids, such as blood, urine and sweat, of CKD patients. Delocalized at-home monitoring of CKD biomarkers via integration of miniaturized, portable, and low cost chemical- and bio-sensors in POC devices, is an emerging approach to improve patients' health monitoring and life quality. The successful monitoring of CKD biomarkers, performed on the different body fluids by means of sensors having strict requirements in term of size, cost, large-scale production capacity, response time and simple operation procedures for use in POC devices, is reported and discussed.
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