4.8 Article

Engineering precision biomaterials for personalized medicine

期刊

SCIENCE TRANSLATIONAL MEDICINE
卷 10, 期 424, 页码 -

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AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/scitranslmed.aam8645

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资金

  1. NIH [1F32HL137256-01, 1R01HL132353-01A1, 5R21AR067469-02]
  2. Burroughs Wellcome Fund Postdoctoral Enrichment Program
  3. Howard Hughes Medical Institute
  4. Burroughs Wellcome Fund Career Award at the Science Interface
  5. Howard Hughes Medical Institute, NSF [1408955]

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As the demand for precision medicine continues to rise, the one-size-fits-all approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.

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