期刊
SCIENCE CHINA-LIFE SCIENCES
卷 61, 期 2, 页码 138-147出版社
SCIENCE PRESS
DOI: 10.1007/s11427-017-9237-4
关键词
NLR; innate immunity; siRNA; miRNA; crop; disease; breeding
类别
资金
- National Natural Science Foundation of China [91440103, 31600984]
- Fundamental Research Funds for the Central Universities [2662014PY008]
Plant resistance (R) proteins are immune receptors that recognize pathogen effectors and trigger rapid defense responses, namely effector-triggered immunity. R protein-mediated pathogen resistance is usually race specific. During plant-pathogen coevolution, plant genomes accumulated large numbers of R genes. Even though plant R genes provide important natural resources for breeding disease-resistant crops, their presence in the plant genome comes at a cost. Misregulation of R genes leads to developmental defects, such as stunted growth and reduced fertility. In the past decade, many microRNAs (miRNAs) have been identified to target various R genes in plant genomes. miRNAs reduce R gene levels under normal conditions and allow induction of R gene expression under various stresses. For these reasons, we consider R genes to be double-edged swords and miRNAs as molecular scabbards. In the present review, we summarize the contributions and potential problems of these swords and discuss the features and production of the scabbards, as well as the mechanisms used to pull the sword from the scabbard when needed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据