相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors
Brian M. Dulmovits et al.
BLOOD (2016)
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin
Takeshi Masuda et al.
SCIENCE (2016)
Delayed globin synthesis leads to excess heme and the macrocytic anemia of Diamond Blackfan anemia and del(5q) myelodysplastic syndrome
Zhantao Yang et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations
Anindita Basak et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
Matthew C. Canver et al.
NATURE (2015)
Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains
Junwei Shi et al.
NATURE BIOTECHNOLOGY (2015)
Induction of fetal hemoglobin through enhanced translation efficiency of γ-globin mRNA
Cynthia K. Hahn et al.
BLOOD (2014)
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
Hiroshi Nishimasu et al.
CELL (2014)
Translational control by heme-regulated eIF2a kinase during erythropoiesis
Jane-Jane Chen
CURRENT OPINION IN HEMATOLOGY (2014)
Easy quantitative assessment of genome editing by sequence trace decomposition
Eva K. Brinkman et al.
NUCLEIC ACIDS RESEARCH (2014)
Eukaryotic initiation factor 2 alpha phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanism
Cynthia K. Hahn et al.
BLOOD (2013)
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
Baohui Chen et al.
CELL (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
Establishment of Immortalized Human Erythroid Progenitor Cell Lines Able to Produce Enucleated Red Blood Cells
Ryo Kurita et al.
PLOS ONE (2013)
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A
Jian Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level
Daniel E. Bauer et al.
SCIENCE (2013)
The Switch from Fetal to Adult Hemoglobin
Vijay G. Sankaran et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2013)
Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis
Noa Novershtern et al.
CELL (2011)
Correction of Sickle Cell Disease in Adult Mice by Interference with Fetal Hemoglobin Silencing
Jian Xu et al.
SCIENCE (2011)
Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6
Jian Xu et al.
GENES & DEVELOPMENT (2010)
A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction
Ajay Perumbeti et al.
BLOOD (2009)
Developmental and species-divergent globin switching are driven by BCL11A
Vijay G. Sankaran et al.
NATURE (2009)
Haem-regulated eIF2α kinase is necessary for adaptive gene expression in erythroid precursors under the stress of iron deficiency
Sijin Liu et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
Deficiency of heme-regulated eIF2α kinase decreases hepcidin expression and splenic iron in HFE-/- mice
Sijin Liu et al.
HAEMATOLOGICA (2008)
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
Juergen Cox et al.
NATURE BIOTECHNOLOGY (2008)
Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A
Vijay G. Sankaran et al.
SCIENCE (2008)
Mortality in sickle cell patients on hydroxyurea therapy
SM Bakanay et al.
BLOOD (2005)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Heme-regulated eIF2α kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency
AP Han et al.
EMBO JOURNAL (2001)