期刊
CORRESPONDANCES EN METABOLISMES HORMONES DIABETES ET NUTRITION
卷 16, 期 10, 页码 290-292出版社
EDIMARK SANTE
关键词
Reactive Oxygen Species; Insulin secretion; beta cell
At low doses, reactive oxygen species (ROS) are physiological signals that are necessary for the harmonious function of beta cells. Hyperglycemia is responsible for oxidative stress, which is not the only cause of the abnormalities of insulin secretion. NADPH oxidase (NOX) contributes to ROS production, and negatively regulates insulin secretion in beta cells.
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