期刊
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
卷 39, 期 8, 页码 1465-1469出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/IAE.0000000000002186
关键词
internal limiting membrane peeling; inverted ILM flap; macular hole; OCT; pars plana vitrectomy
资金
- Grants-in-Aid for Scientific Research [15H04993] Funding Source: KAKEN
Purpose: To evaluate the anatomical and visual outcomes of inverted flap technique of peeling of internal limiting membrane (ILM) versus standard peeling of ILM for macular holes of basal diameter more than 800 mm. Methods: Patients with very large idiopathic macular holes more than 800 mm in basal diameter (ranging from 243 mm to 840 mm in minimum diameter) were retrospectively included in the study. In Group A, 18 eyes of 18 patients underwent ILM peeling using the inverted flap technique. In Group B, 18 eyes of 18 patients underwent conventional ILM peeling. The primary endpoint was the rate of hole closure at 6 months after surgery. The secondary outcome measure was the change in best-corrected visual acuity at 6 months after surgery. Results: There were no significant differences in ocular characteristics of the study groups at baseline except for the age distribution. Mean macular hole diameter was 1,162.8 +/- 206.0 mu m and 1,229.6 +/- 228.1 mu m in Group A and Group B, respectively. The hole closure rate was 88.9% (16/18) in Group A and 77.8% (14/18) in Group B (P = 0.66). The mean gain in best-corrected visual acuity was higher in Group A than in Group B (P = 0.12) at 6 months, but this was not statistically significant. There were no severe ocular adverse events in either group. Conclusion: In this multicenter series, inverted ILM flap technique did not lead to significantly higher anatomical closure rates than conventional ILM peeling in large macular holes more than 800 mm in diameter.
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