期刊
REGENERATIVE MEDICINE
卷 13, 期 2, 页码 207-218出版社
FUTURE MEDICINE LTD
DOI: 10.2217/rme-2017-0112
关键词
bone; human dental pulp; regenerative medicine; stem cells; tissue engineering
资金
- Italian Ministry of University and Research (PON Industrial PhD) [DOT1320875]
The aim of this narrative review is to investigate the implication of mesenchymal stem cells harvested from human dental pulp in in vivo bone tissue regeneration. We focused on studies related to roles of human dental pulp stem cells in in vivo bone regeneration. A total of 1021 studies were identified; after the assessment of eligibility, only 39 studies were included in the review. The evaluated information of the studies regards the experimental strategies (e.g., the isolation method, the scaffold, the in vivo animal models). The overall main evidences highlighted from the analysis are that dental pulp stem cells and human-exfoliated deciduous teeth stem cells supported by a suitable scaffold should be considered a valuable source for bone tissue regeneration.
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