期刊
CLINICAL MEDICINE INSIGHTS-CARDIOLOGY
卷 7, 期 -, 页码 51-57出版社
SAGE PUBLICATIONS LTD
DOI: 10.4137/CMC.S11488
关键词
lipid goal attainment; HMG Co-A reductase inhibitors; secondary prevention; coronary artery disease
资金
- Pfizer, Inc.
Lipid goal attainment studies in Asian patients with acute coronary syndrome (ACS) are limited. The objectives of this study were to determine low-density lipoprotein cholesterol (LDL-C) goal attainment rate at 4 months, and to examine prescription behavior influencing lipid goal attainment in Asian patients with ACS. A retrospective analysis of 267 patients with ACS was performed. The mean follow-up duration was 41.2 +/- 10.7 months. LDL-C goal attainment rate was highest at 4 months (36.7%) but declined progressively throughout follow-up. More than 85% of patients were discharged with equipotent statin dose of 2 (equivalent to simvastatin 20 mg) or less. In patients who did not attain LDL-C goals, the statin dose remained low throughout follow-up because of a lack in responsive dose titration. Aggressive lipid-lowering therapy should be initiated early to improve goal attainment in these high-risk patients.
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