期刊
AIDS AND BEHAVIOR
卷 17, 期 1, 页码 142-147出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10461-011-0124-7
关键词
HIV; AIDS; Substance use; Adherence; Cannabis
资金
- NIAID NIH HHS [R01AI41413, P30 AI050410, AI38858, AI069419] Funding Source: Medline
- NIDA NIH HHS [R01DA13826, K02DA017277, R01DA15215, R01 DA015215, R01DA015679, R01DA11869] Funding Source: Medline
- NIMH NIH HHS [R01 MH61173, K23MH01862, R01MH58986, R01 MH054907, R01MH078773, R01 MH078773, R01MH61695, R01MH01584, R01MH54907, R01 MH068197, R01MH68197, P01MH49548, P30 MH043520] Funding Source: Medline
- NINR NIH HHS [R01NR04749] Funding Source: Medline
- CDC HHS [CC99-SD003, CC02-SD-003] Funding Source: Medline
To determine the association between individual substances of abuse and antiretroviral adherence, analyses require a large sample assessed using electronic data monitoring (EDM). In this analysis, EDM data from 1,636 participants in 12 US adherence-focused studies were analyzed to determine the associations between recent use of various substances and adherence during the preceding 4 weeks. In bivariate analyses comparing adherence among patients who had used a specific substance to those who had not, adherence was significantly lower among those who had recently used cocaine, other stimulants or heroin but not among those who had used cannabis or alcohol. In multivariate analyses controlling for sociodemographics, amount of alcohol use and recent use of any alcohol, cocaine, other stimulants and heroin each was significantly negatively associated with adherence. The significant associations of cocaine, other stimulants, heroin, and alcohol use with adherence suggest that these are important substances to target with adherence-focused interventions.
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