相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。mTORC1 and mTORC2 as regulators of cell metabolism in immunity
Monika Linke et al.
FEBS LETTERS (2017)
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system
Sebastian I. Arriola Apelo et al.
AGING CELL (2016)
Regulation of mTOR Activity in Snell Dwarf and GH Receptor Gene-Disrupted Mice
Graham Dominick et al.
ENDOCRINOLOGY (2015)
Deletion of Rictor in Brain and Fat Alters Peripheral Clock Gene Expression and Increases Blood Pressure
Katja Draegert et al.
HYPERTENSION (2015)
Rictor/mTORC2 Pathway in Oocytes Regulates Folliculogenesis, and Its Inactivation Causes Premature Ovarian Failure
Zhenguo Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation
Chang-Jun Li et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2
Christl Gaubitz et al.
MOLECULAR CELL (2015)
Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan
Dudley W. Lamming et al.
AGING CELL (2014)
mTOR inhibition improves immune function in the elderly
Joan B. Mannick et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Gene expression analysis of mTOR pathway: association with human longevity
Willemijn M. Passtoors et al.
AGING CELL (2013)
Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive
Dudley W. Lamming et al.
AGING CELL (2013)
Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice
Yimin Fang et al.
CELL METABOLISM (2013)
Mechanistic Target of Rapamycin Complex 2 Protects the Heart From Ischemic Damage
Mirko Voelkers et al.
CIRCULATION (2013)
Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology
Venus Thomanetz et al.
JOURNAL OF CELL BIOLOGY (2013)
mTOR is a key modulator of ageing and age-related disease
Simon C. Johnson et al.
NATURE (2013)
SOMATOTROPIC SIGNALING: TRADE-OFFS BETWEEN GROWTH, REPRODUCTIVE DEVELOPMENT, AND LONGEVITY
Andrzej Bartke et al.
PHYSIOLOGICAL REVIEWS (2013)
A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: 13-arrestin 1 protein levels in depression and treatment
Indira Mendez-David et al.
FRONTIERS IN PHARMACOLOGY (2013)
Metabolic effects of intra-abdominal fat in GHRKO mice
Michal M. Masternak et al.
AGING CELL (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
Dudley W. Lamming et al.
SCIENCE (2012)
Raptor and Rheb Negatively Regulate Skeletal Myogenesis through Suppression of Insulin Receptor Substrate 1 (IRS1)
Yejing Ge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice
Markus Goedel et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
mTOR couples cellular nutrient sensing to organismal metabolic homeostasis
Jessica J. Howell et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2011)
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
Alexander A. Soukas et al.
GENES & DEVELOPMENT (2009)
Reduced Incidence and Delayed Occurrence of Fatal Neoplastic Diseases in Growth Hormone Receptor/Binding Protein Knockout Mice
Yuji Ikeno et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2009)
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
David E. Harrison et al.
NATURE (2009)
mTOR complex 2 in adipose tissue negatively controls whole-body growth
Nadine Cybulski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
Colin Selman et al.
SCIENCE (2009)
mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
Chong Chen et al.
SCIENCE SIGNALING (2009)
PLD regulates myoblast differentiation through the mTOR-IGF2 pathway
Mee-Sup Yoon et al.
JOURNAL OF CELL SCIENCE (2008)
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity
Anil Kumar et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice
FP Dominici et al.
JOURNAL OF ENDOCRINOLOGY (2000)
Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
KT Coschigano et al.
ENDOCRINOLOGY (2000)