相关参考文献
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Olga Alekhina et al.
JOURNAL OF CELL SCIENCE (2017)
Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex
Max Rodnick-Smith et al.
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Identification of an ATP-controlled allosteric switch that controls actin filament nucleation by Arp2/3 complex
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Nature Communications (2016)
Kojak: Efficient Analysis of Chemically Cross-Linked Protein Complexes
Michael R. Hoopmann et al.
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Regulation of outer kinetochore Ndc80 complex-based microtubule attachments by the central kinetochore Mis12/MIND complex
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The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling
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Arp2/3-mediated F-actin formation controls regulated exocytosis in vivo
Duy T. Tran et al.
NATURE COMMUNICATIONS (2015)
Crystals of the Arp2/3 complex in two new space groups with structural information about actin-related protein 2 and potential WASP binding sites
Christopher T. Jurgenson et al.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2015)
Structural analysis of the transitional state of Arp2/3 complex activation by two actin-bound WCAs
Malgorzata Boczkowska et al.
NATURE COMMUNICATIONS (2014)
Small Molecules CK-666 and CK-869 Inhibit Actin-Related Protein 2/3 Complex by Blocking an Activating Conformational Change
Byron Hetrick et al.
CHEMISTRY & BIOLOGY (2013)
Insertions within the Actin Core of Actin-related Protein 3 (Arp3) Modulate Branching Nucleation by Arp2/3 Complex
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JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
New insights into the regulation and cellular functions of the ARP2/3 complex
Jeremy D. Rotty et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging
Benjamin A. Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP
Luke A. Helgeson et al.
ELIFE (2013)
Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation
Benjamin A. Smith et al.
ELIFE (2013)
Arp2/3 Is Critical for Lamellipodia and Response to Extracellular Matrix Cues but Is Dispensable for Chemotaxis
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Three-dimensional reconstructions of Arp2/3 complex with bound nucleation promoting factors
Xiao-Ping Xu et al.
EMBO JOURNAL (2012)
Mechanism of a Concentration-dependent Switch between Activation and Inhibition of Arp2/3 Complex by Coronin
Su-Ling Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex
Shih-Chieh Ti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Arp2/3 complex is bound and activated by two WASP proteins
Shae B. Padrick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A Primer-Based Mechanism Underlies Branched Actin Filament Network Formation and Motility
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CURRENT BIOLOGY (2010)
WASP Family Proteins: Their Evolution and Its Physiological Implications
Douwe M. Veltman et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
A nucleator arms race: cellular control of actin assembly
Kenneth G. Campellone et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Nucleotide- and Activator-Dependent Structural and Dynamic Changes of Arp2/3 Complex Monitored by Hydrogen/Deuterium Exchange and Mass Spectrometry
Wendy D. Zencheck et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
The structural basis of actin filament branching by the Arp2/3 complex
Isabelle Rouiller et al.
JOURNAL OF CELL BIOLOGY (2008)
Nucleotide-mediated conformational changes of monomeric actin and Arp3 studied by molecular dynamics simulations
Paul Dalhaimer et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
X-ray scattering study of activated Arp2/3 complex with bound actin-WCA
Malgorzata Boczkowska et al.
STRUCTURE (2008)
Pathway of actin filament branch formation by Arp2/3 complex
Christopher C. Beltzner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Insiahts into the influence of nucleotides on actin family proteins from seven structures of Arp2/3 complex
Brad J. Nolen et al.
MOLECULAR CELL (2007)
The ARP2/3 complex: an actin nucleator comes of age
Erin D. Goley et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Actin binding to the central domain of WASP/Scar proteins plays a critical role in the activation of the arp2/3 complex
AE Kelly et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
NMR analyses of the activation of the Arp2/3 complex by neuronal Wiskott-Aldrich syndrome protein
M Kreishman-Deitrick et al.
BIOCHEMISTRY (2005)
Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly
D Chereau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function
AC Martin et al.
JOURNAL OF CELL BIOLOGY (2005)
Conformational changes in the Arp2/3 complex leading to actin nucleation
AA Rodal et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Activation of Arp2/3 complex: Addition of the first subunit of the new filament by a WASP protein triggers rapid ATP hydrolysis on Arp2
MJ Dayel et al.
PLOS BIOLOGY (2004)
Identification of functionally important residues of Arp2/3 complex by analysis of homology models from diverse species
CC Beltzner et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Structural basis of actin sequestration by thymosin-β4:: implications for WH2 proteins
E Irobi et al.
EMBO JOURNAL (2004)
Critical conformational changes in the Arp2/3 complex are induced by nucleotide and nucleation promoting factor
ED Goley et al.
MOLECULAR CELL (2004)
A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex
SC Panchal et al.
NATURE STRUCTURAL BIOLOGY (2003)
Interaction of cortactin and N-WASp with Arp2/3 complex
AM Weaver et al.
CURRENT BIOLOGY (2002)
Different WASP family proteins stimulate different Arp2/3 complex-dependent actin-nucleating activities
J Zalevsky et al.
CURRENT BIOLOGY (2001)
Crystal structure of Arp2/3 complex
RC Robinson et al.
SCIENCE (2001)
Activation of the Arp2/3 complex by the Listeria ActA protein -: ActA binds two actin monomers and three subunits of the Arp2/3 complex
J Zalevsky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex
JB Marchand et al.
NATURE CELL BIOLOGY (2001)
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