期刊
PHARMACOLOGICAL REPORTS
卷 65, 期 2, 页码 313-335出版社
SPRINGER HEIDELBERG
DOI: 10.1016/S1734-1140(13)71007-7
关键词
isatin; derivatives; DNA and HSA binding; antimicrobial; anticancer; anticonvulsant; antioxidant
资金
- Razi University Research Center
Isatin, 1H-indole-2,3-dione, is a heterocyclic compound of significant importance in medicinal chemistry. It is a synthetically versatile molecule, a precursor for a large number of pharmacologically active compounds. Isatin and its derivatives have aroused great attention in recent years due to their wide variety of biological activities, relevant to application as insecticides and fungicides and in a broad range of drug therapies, including anticancer drugs, antibiotics and antidepressants. The purpose of this review is to provide an overview of the pharmacological activities of isatin and its synthetic and natural derivatives. Molecular modifications to tailor the properties of isatin and its derivatives are also discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据