期刊
POLYMER CHEMISTRY
卷 9, 期 26, 页码 3667-3673出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8py00733k
关键词
-
资金
- National Natural Science Foundation of China [51733003, 21674025, 51473038]
Hydrogen bonding reinforcement via copolymerization of N-acryloylglycinamide (NAGA) with methacrylic acid (MAA) is employed as a strategy to improve the upper critical solution temperature (UCST) to a biologically relevant range. P(NAGA-co-MAA) copolymers with MAA molar fraction in the range of 1-81 mol% are synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. The UCST (3.5-37.5 degrees C) of the copolymers scales with MAA molar fraction in the range of 10-60 mol% when measured at pH 4 and 1 wt% concentration. Using a copolymer with a suitably high UCST as a macromolecular chain transfer agent, doubly thermoresponsive nanogels consisting of P(NAGA-co-MAA) copolymer as the shell and cross-linked poly(N-isopropylacrylamide) (PNIPAM) as the core are synthesized via RAFT aqueous dispersion polymerization. The nanogels show distinct thermal transitions with both upper and lower critical solution temperatures (UCST and LCST).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据