期刊
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
卷 2, 期 4, 页码 -出版社
WILEY
DOI: 10.1038/psp.2013.14
关键词
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Population pharmacokinetic models are used to describe the time course of drug exposure in patients and to investigate sources of variability in patient exposure. They can be used to simulate alternative dose regimens, allowing for informed assessment of dose regimens before study conduct. This paper is the second in a three-part series, providing an introduction into methods for developing and evaluating population pharmacokinetic models. Example model files are available in the Supplementary Data online.
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