Three new nortriterpenoids from the rattan stems of Schisandra chinensis

Three new nortriterpenoids, schindilactones L and M (1-2) and wuweizidilactone S (3), along with five known nortriterpenoids, schindilactone G (4), wuweizidilactone A (5), wuweizidilactone L (6), wuweizidilactone C (7) and pre-schisanartanin (8), were isolated from the rattan stems of Schisandra chinensis. The structure of the new compounds were elucidated by spectroscopic methods, including one and two-dimensional NMR as well as high-resolution mass spectrometry. All of the compounds were evaluated for their cytotoxicities against human Hela cancer cell lines in vitro; none of them showed significant activities.