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Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
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LANCET (2010)
Regulatory T cells in many flavors control asthma
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MUCOSAL IMMUNOLOGY (2010)
Control of RSV-induced lung injury by alternatively activated macrophages is IL-4Rα-, TLR4-, and IFN-β-dependent
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MUCOSAL IMMUNOLOGY (2010)
Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4
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MUCOSAL IMMUNOLOGY (2010)
Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Resolvin D1 binds human phagocytes with evidence for proresolving receptors
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Proteolytic regulatory mechanism of chemerin bioactivity
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ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2009)
15-Epi-lipoxin A4 Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury
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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)
Effects of Fat and Fatty Acid Intake on Inflammatory and Immune Responses: A Critical Review
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ANNALS OF NUTRITION AND METABOLISM (2009)
Activation of Polyisoprenyl Diphosphate Phosphatase 1 Remodels Cellular Presqualene Diphosphate
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BIOCHEMISTRY (2009)
CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury
Franco R. D'Alessio et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions
Charles N. Serhan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
ATLa, an Aspirin-Triggered Lipoxin A4 Synthetic Analog, Prevents the Inflammatory and Fibrotic Effects of Bleomycin-Induced Pulmonary Fibrosis
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JOURNAL OF IMMUNOLOGY (2009)
Synthesis of Lipoxin A4 by 5-Lipoxygenase Mediates PPARγ-Dependent, Neuroprotective Effects of Rosiglitazone in Experimental Stroke
Monica Sobrado et al.
JOURNAL OF NEUROSCIENCE (2009)
Small GTPases in mechanosensitive regulation of endothelial barrier
Konstantin G. Birukov
MICROVASCULAR RESEARCH (2009)
Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis
Matthew Spite et al.
NATURE (2009)
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma
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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)
Serum amyloid A is a biomarker of acute exacerbations of chronic obstructive pulmonary disease
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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)
Resolvin E1 dampens airway inflammation and hyperresponsiveness in a murine model of asthma
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Synthetic chemerin-derived peptides suppress inflammation through ChemR23
Jenna L. Cash et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses
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JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Rapid Appearance of Resolvin Precursors in Inflammatory Exudates: Novel Mechanisms in Resolution
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JOURNAL OF IMMUNOLOGY (2008)
Resolvin E1 regulates interleukin 23, interferon-γ and lipoxin A4 to promote the resolution of allergic airway inflammation
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NATURE IMMUNOLOGY (2008)
Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism
Bruce D. Levy et al.
FASEB JOURNAL (2007)
Resolvin E1 promotes mucosal surface clearance of neutrophils: a new paradigm for inflammatory resolution
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FASEB JOURNAL (2007)
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
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JOURNAL OF IMMUNOLOGY (2007)
Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils:: A novel mechanism for resolution of inflammation
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JOURNAL OF IMMUNOLOGY (2007)
Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Resolvin E1 and protectin D1 activate inflammation-resolution programmes
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NATURE (2007)
Resolvin D1 and its aspirin-triggered 17R epimer -: Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation
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JOURNAL OF IMMUNOLOGY (2007)
Posttreatment with aspirin-triggered lipoxin A4 analog attenuates lipopolysaccharide-induced acute lung injury in mice:: The role of heme oxygenase-1
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ANESTHESIA AND ANALGESIA (2007)
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness
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JOURNAL OF IMMUNOLOGY (2007)
Resolution phase of inflammation: Novel endogenous anti-inflammatory and proresolving lipid mediators and pathways
Charles N. Serhan
ANNUAL REVIEW OF IMMUNOLOGY (2007)
Glucocorticoids co-interact with lipoxin A(4) via lipoxin A(4) receptor (ALX) up-regulation
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BIOMEDICINE & PHARMACOTHERAPY (2007)
Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation
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JOURNAL OF CLINICAL INVESTIGATION (2006)
Glucocorticoid upregulation of the annexin-A1 receptor in leukocytes
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Resolvin E2: Identification and anti-inflammatory actions: Pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis
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CHEMISTRY & BIOLOGY (2006)
Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression
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NATURE IMMUNOLOGY (2006)
Resolvin D series and Protectin D1 mitigate acute kidney injury
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JOURNAL OF IMMUNOLOGY (2006)
Enhanced Ca2+ sensitivity in hyperresponsive cultured bronchi is mediated by TNFα and NF-κB
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CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2006)
Augmentation of myocardial production of 15-epi-lipoxin-A4 by pioglitazone and atorvastatin in the rat
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CIRCULATION (2006)
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
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NATURE REVIEWS GENETICS (2006)
Identification and functional characterization of a presqualene diphosphate phosphatase
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Lipoxin A4 regulates bronchial epithelial cell responses to acid injury
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AMERICAN JOURNAL OF PATHOLOGY (2006)
Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienes
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JOURNAL OF IMMUNOLOGY (2006)
RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis
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FASEB JOURNAL (2006)
Aspirin-triggered Lipoxin A(4) inhibition of VEGF-induced endothelial cell migration involves actin polymerization and focal adhesion assembly
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ONCOGENE (2006)
The lipoxin receptor ALX: Potent ligand-specific and stereoselective actions in vivo
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PHARMACOLOGICAL REVIEWS (2006)
Lipoxin A(4) inhibits proliferation of human lung fibroblasts induced by connective tissue growth factor
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AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2006)
The docosatriene Protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cyclooxygenase- and lipoxygenase-derived eicosanoids in bronchoalveolar lavage fluid from patients with scleroderma lung disease - An imbalance between proinflammatory and antiinflammatory lipid mediators
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ARTHRITIS AND RHEUMATISM (2005)
Intake frequency of fish and serum levels of long-chain n-3 fatty acids: A cross-sectional study within the Japan Collaborative Cohort Study
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JOURNAL OF EPIDEMIOLOGY (2005)
Incidence and outcomes of acute lung injury
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NEW ENGLAND JOURNAL OF MEDICINE (2005)
Diminished lipoxin biosynthesis in severe asthma
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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
Involvement of the Rho-kinase/myosin light chain kinase pathway on human monocyte chemotaxis induced by ATL-1, an aspirin-triggered lipoxin A4 synthetic analog
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JOURNAL OF IMMUNOLOGY (2005)
Aging is characterized by a profound reduction in anti-inflammatory lipoxin A4 levels
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EXPERIMENTAL GERONTOLOGY (2005)
Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production
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JOURNAL OF CLINICAL INVESTIGATION (2005)
Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury
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JOURNAL OF IMMUNOLOGY (2005)
Molecular circuits of resolution: Formation and actions of resolvins and protectins
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JOURNAL OF IMMUNOLOGY (2005)
Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1
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JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Severe asthma is associated with a loss of LX4, an endogenous anti-inflammatory compound
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway
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NATURE IMMUNOLOGY (2004)
Association of cystic fibrosis with abnormalities in fatty acid metabolism
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NEW ENGLAND JOURNAL OF MEDICINE (2004)
Expression of cytochromes P450 1A1 and 1B1 in human lung from smokers, non-smokers, and ex-smokers
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TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration
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BRITISH JOURNAL OF PHARMACOLOGY (2004)
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
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MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2004)
Neuroprotectin D1: A docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Aspirin triggers anti inflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids
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JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-α secretion from human T cells
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JOURNAL OF IMMUNOLOGY (2003)
A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils
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FASEB JOURNAL (2003)
A novel rat lipoxin A4 receptor that is conserved in structure and function
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BRITISH JOURNAL OF PHARMACOLOGY (2003)
Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells -: Autacoids in anti-inflammation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
International union of pharmacology - XXXVII. Nomenclature for leukotriene and lipoxin receptors
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PHARMACOLOGICAL REVIEWS (2003)
Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R
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BLOOD (2003)
Parasite-induced lipoxin A4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection
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JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor
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NATURE MEDICINE (2002)
Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
CN Serhan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation:: Stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo
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JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4
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NATURE MEDICINE (2002)
Blood levels of long-chain n-3 fatty acids and the risk of sudden death.
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NEW ENGLAND JOURNAL OF MEDICINE (2002)
The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity
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NATURE IMMUNOLOGY (2002)
Lipid mediator class switching during acute inflammation: signals in resolution
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NATURE IMMUNOLOGY (2001)
Selectivity of recombinant human leukotriene D-4, leukotriene B-4, and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses
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AMERICAN JOURNAL OF PATHOLOGY (2001)
Mutations of serine 236-237 and tyrosine 302 residues in the human lipoxin A4 receptor intracellular domains result in sustained signaling
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BIOCHEMISTRY (2000)
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing
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JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Oxidoreductases in lipoxin A4 metabolic inactivation -: A novel role for 15-oxoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation
CB Clish et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Activation of lipoxin A4 receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation
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JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Cutting edge:: Lipoxin (LX) A4 and aspirin-triggered 15-Epi-LXA4 block allergen-induced eosinophil trafficking
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JOURNAL OF IMMUNOLOGY (2000)
Cutting edge: Lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages
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JOURNAL OF IMMUNOLOGY (2000)