相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Regionally compartmentalized resident memory T cells mediate naturally acquired protection against pneumococcal pneumonia
N. M. S. Smith et al.
MUCOSAL IMMUNOLOGY (2018)
Burden of Pneumonia-Associated Hospitalizations United States, 2001-2014
Brandon H. Hayes et al.
CHEST (2018)
Mechanisms of lung aging
Christina Brandenberger et al.
CELL AND TISSUE RESEARCH (2017)
Gut-lung axis: The microbial contributions and clinical implications
Yang He et al.
CRITICAL REVIEWS IN MICROBIOLOGY (2017)
Cross-protective mucosal immunity mediated by memory Th17 cells against Streptococcus pneumoniae lung infection
Y. Wang et al.
MUCOSAL IMMUNOLOGY (2017)
The respiratory tract microbiome and lung inflammation: a two-way street
G. B. Huffnagle et al.
MUCOSAL IMMUNOLOGY (2017)
Liver - guardian, modifier and target of sepsis
Pavel Strnad et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
Emerging pathogenic links between microbiota and the gut-lung axis
Kurtis F. Budden et al.
NATURE REVIEWS MICROBIOLOGY (2017)
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators
Becca A. Flitter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Selective decontamination of the digestive tract halves the prevalence of ventilator-associated pneumonia compared to selective oral decontamination
Lieuwe D. Bos et al.
INTENSIVE CARE MEDICINE (2017)
Role of the phagosomal redox-sensitive TRP channel TRPM2 in regulating bactericidal activity of macrophages
Anke Di et al.
JOURNAL OF CELL SCIENCE (2017)
Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells
Gregory A. Wasserman et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Capacity of Pneumococci to Activate Macrophage Nuclear Factor κB: Influence on Necroptosis and Pneumonia Severity
Fadie T. Coleman et al.
JOURNAL OF INFECTIOUS DISEASES (2017)
Searching for a Lifeline: Transcriptome Profiling Studies of Influenza Susceptibility and Resistance
Lester Kobzik
JOURNAL OF INNATE IMMUNITY (2017)
Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study
Jingjing Quan et al.
LANCET INFECTIOUS DISEASES (2017)
Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study
Yang Wang et al.
LANCET INFECTIOUS DISEASES (2017)
Intrinsic 4-1BB signals are indispensable for the establishment of an influenza-specific tissue-resident memory CD8 T-cell population in the lung
A. C. Zhou et al.
MUCOSAL IMMUNOLOGY (2017)
IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and - negative bacterial pneumonia
M. A. Kovach et al.
MUCOSAL IMMUNOLOGY (2017)
The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors
Emma Lefrancais et al.
NATURE (2017)
The microbiota of the respiratory tract: gatekeeper to respiratory health
Wing Ho Man et al.
NATURE REVIEWS MICROBIOLOGY (2017)
Tight Glycemic Control in Critically Ill Children
M. S. D. Agus et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Risk factors for child pneumonia - focus on the Western Pacific Region
T. K. P. Nguyen et al.
PAEDIATRIC RESPIRATORY REVIEWS (2017)
Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells
Lidia Bosurgi et al.
SCIENCE (2017)
Local amplifiers of IL-4Rα-mediated macrophage activation promote repair in lung and liver
Carlos M. Minutti et al.
SCIENCE (2017)
Lymphocyte generation and population homeostasis throughout life
Rolando E. Yanes et al.
SEMINARS IN HEMATOLOGY (2017)
Naturally Acquired Human Immunity to Pneumococcus Is Dependent on Antibody to Protein Antigens
Robert Wilson et al.
PLOS PATHOGENS (2017)
Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice
John C. Gomez et al.
SCIENTIFIC REPORTS (2017)
Rapid Pathogen Identification in Bacterial Pneumonia Using Real-Time Metagenomics
Kathryn M. Pendleton et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages
Martin A. Bewley et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Myeloid-epithelial cross talk coordinates synthesis of the tissue-protective cytokine leukemia inhibitory factor during pneumonia
Katrina E. Traber et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2017)
Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling
Luis F. Reyes et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Early Expansion of Circulating Granulocytic Myeloid-derived Suppressor Cells Predicts Development of Nosocomial Infections in Patients with Sepsis
Fabrice Uhel et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Immunomodulators targeting MARCO expression improve resistance to postinfluenza bacterial pneumonia
Muzo Wu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2017)
Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
Andrew J. Lechner et al.
CELL STEM CELL (2017)
Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia
Kathryn R. Michels et al.
JCI INSIGHT (2017)
Epigenetic and Transcriptomic Regulation of Lung Repair during Recovery from Influenza Infection
Derek A. Pociask et al.
AMERICAN JOURNAL OF PATHOLOGY (2017)
Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages
Jamil Jubrail et al.
CELLULAR MICROBIOLOGY (2016)
The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia
Tim J. Schuijt et al.
GUT (2016)
Expression of activation-induced cytidine deaminase enhances the clearance of pneumococcal pneumonia: evidence of a subpopulation of protective anti-pneumococcal B1a cells
Natsuo Yamamoto et al.
IMMUNOLOGY (2016)
Natural Killer Cells and Innate Interferon Gamma Participate in the Host Defense against Respiratory Vaccinia Virus Infection
Georges Abboud et al.
JOURNAL OF VIROLOGY (2016)
IFN-γ induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense
S. Cai et al.
MUCOSAL IMMUNOLOGY (2016)
Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection
M. Dudek et al.
MUCOSAL IMMUNOLOGY (2016)
Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues
Joseph J. C. Thome et al.
NATURE MEDICINE (2016)
Enhanced resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming
F. R. D'Alessio et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2016)
Innate Lymphoid Cells Are the Predominant Source of IL-17A during the Early Pathogenesis of Acute Respiratory Distress Syndrome
Roshell Muir et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients
Lonneke A. van Vught et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
Immune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells
Meenal Sinha et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2016)
Persistent Pathology in Influenza-Infected Mouse Lungs
Cindy M. Kanegai et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2016)
Epithelial Cell-Derived Secreted and Transmembrane 1a Signals to Activated Neutrophils during Pneumococcal Pneumonia
Hirofumi Kamata et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2016)
Mouse Modeling of Obese Lung Disease Insights and Caveats
Benjamin T. Suratt
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2016)
Long-Term Persistence of Donor Alveolar Macrophages in Human Lung Transplant Recipients That Influences Donor-Specific Immune Responses
D. K. Nayak et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2016)
The Microbiome and the Respiratory Tract
Robert P. Dickson et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 78 (2016)
Inducible epithelial resistance protects mice against leukemia-associated pneumonia
Miguel M. Leiva-Juarez et al.
BLOOD (2016)
Risk factors for community-acquired pneumonia in children under five years of age in the post-pneumococcal conjugate vaccine era in Brazil: a case control study
Eduardo Jorge da Fonseca Lima et al.
BMC PEDIATRICS (2016)
Innate Lymphocyte/Ly6Chi Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance
Huizhong Xiong et al.
CELL (2016)
IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae
Kong Chen et al.
CELL HOST & MICROBE (2016)
Efficacy and Safety of Corticosteroids for Community-Acquired Pneumonia A Systematic Review and Meta-Analysis
You-Dong Wan et al.
CHEST (2016)
The Gut as the Motor of Multiple Organ Dysfunction in Critical Illness
Nathan J. Klingensmith et al.
CRITICAL CARE CLINICS (2016)
High-sensitivity cardiac troponin I and incident coronary heart disease among asymptomatic older adults
Carlos Iribarren et al.
HEART (2016)
Neutrophil swarming: an essential process of the neutrophil tissue response
Korbinian Kienle et al.
IMMUNOLOGICAL REVIEWS (2016)
MHC class I-related molecule, MR1, and mucosal-associated invariant T cells
Katarzyna Franciszkiewicz et al.
IMMUNOLOGICAL REVIEWS (2016)
Infiltrated Macrophages Die of Pneumolysin-Mediated Necroptosis following Pneumococcal Myocardial Invasion
Ryan P. Gilley et al.
INFECTION AND IMMUNITY (2016)
Interleukin-17 Is Required for Control of Chronic Lung Infection Caused by Pseudomonas aeruginosa
Hannah K. Bayes et al.
INFECTION AND IMMUNITY (2016)
Infectious Disease Mortality Trends in the United States, 1980-2014
Victoria Hansen et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Immunosuppression and Secondary Infection in Sepsis Part, Not All, of the Story
Derek C. Angus et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Trend in Ventilator-Associated Pneumonia Rates Between 2005 and 2013
Mark L. Metersky et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis
Lonneke A. van Vught et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Mervyn Singer et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries
Giacomo Bellani et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Respiratory syncytial virus infection activates IL-13-producing group 2 innate lymphoid cells through thymic stromal lymphopoietin
Matthew T. Stier et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)
Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection
David J. DiLillo et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection
Christin Peteranderl et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance
Shiki Takamura et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells
Alejo Chorny et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Direct IL-6 Signals Maximize Protective Secondary CD4 T Cell Responses against Influenza
Tara M. Strutt et al.
JOURNAL OF IMMUNOLOGY (2016)
Critical Role of IL-22/IL22-RA1 Signaling in Pneumococcal Pneumonia
Giraldina Trevejo-Nunez et al.
JOURNAL OF IMMUNOLOGY (2016)
Generation and Protective Ability of Influenza Virus-Specific Antibody-Dependent Cellular Cytotoxicity in Humans Elicited by Vaccination, Natural Infection, and Experimental Challenge
Sinthujan Jegaskanda et al.
JOURNAL OF INFECTIOUS DISEASES (2016)
Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study
Yi-Yun Liu et al.
LANCET INFECTIOUS DISEASES (2016)
The evolution of nasal immune systems in vertebrates
Ali Sepahi et al.
MOLECULAR IMMUNOLOGY (2016)
Normalizing the environment recapitulates adult human immune traits in laboratory mice
Lalit K. Beura et al.
NATURE (2016)
Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells
Pleun Hombrink et al.
NATURE IMMUNOLOGY (2016)
The development and maintenance of resident macrophages
Elisa Gomez Perdiguero et al.
NATURE IMMUNOLOGY (2016)
Risk Factors for Presumed Bacterial Pneumonia Among HIV-uninfected Children Hospitalized in Soweto, South Africa
Jennifer R. Verani et al.
PEDIATRIC INFECTIOUS DISEASE JOURNAL (2016)
INNATE IMMUNE SIGNALING ACTIVATED BY MDR BACTERIA IN THE AIRWAY
Dane Parker et al.
PHYSIOLOGICAL REVIEWS (2016)
Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation
Liyen Loh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Potent protection against H5N1 and H7N9 influenza via childhood hemagglutinin imprinting
Katelyn M. Gostic et al.
SCIENCE (2016)
Pulmonary neuroendocrine cells function as airway sensors to control lung immune response
Kelsey Branchfield et al.
SCIENCE (2016)
Trained immunity: A program of innate immune memory in health and disease
Mihai G. Netea et al.
SCIENCE (2016)
Macrophage-epithelial interactions in pulmonary alveoli
Jahar Bhattacharya et al.
SEMINARS IN IMMUNOPATHOLOGY (2016)
Surfactant Proteins SP-A and SP-D Ameliorate Pneumonia Severity and Intestinal Injury in a Murine Model of Staphylococcus Aureus Pneumonia
Xianjin Du et al.
SHOCK (2016)
Long-term persistence of human donor alveolar macrophages in lung transplant recipients
Ibon Eguiluz-Gracia et al.
THORAX (2016)
Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans
Raffael Nachbagauer et al.
MBIO (2016)
Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner
Caitlin E. Mullarkey et al.
MBIO (2016)
iNKT Cell Emigration out of the Lung Vasculature Requires Neutrophils and Monocyte-Derived Dendritic Cells in Inflammation
Ajitha Thanabalasuriar et al.
CELL REPORTS (2016)
TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity
Alicja Puchta et al.
PLOS PATHOGENS (2016)
T-Cell immunity to influenza in Older Adults: A Pathophysiological Framework for Development of More effective vaccines
Janet E. McElhaney et al.
FRONTIERS IN IMMUNOLOGY (2016)
α1-Antitrypsin deficiency
Catherine M. Greene et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome
Robert P. Dickson et al.
NATURE MICROBIOLOGY (2016)
Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype
Leopoldo N. Segal et al.
NATURE MICROBIOLOGY (2016)
Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung
Katrien C. De Grove et al.
PLOS ONE (2016)
Specialized pro-resolving mediators: endogenous regulators of infection and inflammation
Maria C. Basil et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Microbial Etiology of Pneumonia: Epidemiology, Diagnosis and Resistance Patterns
Catia Cilloniz et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Hyperleptinemia is associated with impaired pulmonary host defense
Niki D. J. Ubags et al.
JCI INSIGHT (2016)
The Role of Viral, Host, and Secondary Bacterial Factors in Influenza Pathogenesis
John C. Kash et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
Platelets in the pathogenesis of acute respiratory distress syndrome
Hemang Yadav et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Update in Sepsis and Acute Kidney Injury 2014
Frederique Schortgen et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)
Ten-Year Mortality after Community-acquired Pneumonia A Prospective Cohort
Dean T. Eurich et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)
Platelet Activation and Aggregation Promote Lung Inflammation and Influenza Virus Pathogenesis
Vuong Ba Le et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)
The Lung-Liver Axis: A Requirement for Maximal Innate Immunity and Hepatoprotection during Pneumonia
Kristie L. Hilliard et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2015)
Induction of STAT3-Dependent CXCL5 Expression and Neutrophil Recruitment by Oncostatin-M during Pneumonia
Katrina E. Traber et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2015)
Mechanisms of Interferon-γ Production by Neutrophils and Its Function during Streptococcus pneumoniae Pneumonia
John C. Gomez et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2015)
Mechanisms of Bacterial Colonization of the Respiratory Tract
Steven J. Siegel et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 69 (2015)
Dynamics of Lung Defense in Pneumonia: Resistance, Resilience, and Remodeling
Lee J. Quinton et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 77 (2015)
Rates of pneumonia among children and adults with chronic medical conditions in Germany
Stephen I. Pelton et al.
BMC INFECTIOUS DISEASES (2015)
Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors
Simon Haas et al.
CELL STEM CELL (2015)
Distinct Molecular Phenotypes of Direct vs Indirect ARDS in Single-Center and Multicenter Studies
Carolyn S. Calfee et al.
CHEST (2015)
Understanding Lung Immunopathology Caused by the Human Metapneumovirus: Implications for Rational Vaccine Design
Christian E. Palavecino et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2015)
Targeting antimicrobial-resistant bacterial respiratory tract pathogens: it is time to 'get smart'
Boeun Lee et al.
CURRENT OPINION IN PULMONARY MEDICINE (2015)
T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate
Laura K. Mackay et al.
IMMUNITY (2015)
MR1-restricted mucosal associated invariant T (MAIT) cells in the immune response to Mycobacterium tuberculosis
Marielle C. Gold et al.
IMMUNOLOGICAL REVIEWS (2015)
Activation of Hepatic STAT3 Maintains Pulmonary Defense during Endotoxemia
Kristie L. Hilliard et al.
INFECTION AND IMMUNITY (2015)
Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease
Agnieszka Rynda-Apple et al.
INFECTION AND IMMUNITY (2015)
Distinct Contributions of Neutrophils and CCR2+ Monocytes to Pulmonary Clearance of Different Klebsiella pneumoniae Strains
Huizhong Xiong et al.
INFECTION AND IMMUNITY (2015)
Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination
Carlos G. Grijalva et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)
Association Between Hospitalization for Pneumonia and Subsequent Risk of Cardiovascular Disease
Vicente F. Corrales-Medina et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)
Readmission Diagnoses After Hospitalization for Severe Sepsis and Other Acute Medical Conditions
Hallie C. Prescott et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)
Effect of Corticosteroids on Treatmmt Failure Among Hospitalized Patients With Severe Community-Acquired Pneumonia and High Inflammatory Response A Randomized Clinical Trial
Antoni Torres et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)
Airway-Resident Memory CD8 T Cells Provide Antigen-Specific Protection against Respiratory Virus Challenge through Rapid IFN-γ Production
Sean R. McMaster et al.
JOURNAL OF IMMUNOLOGY (2015)
Effect of Preexisting Serum and Mucosal Antibody on Experimental Respiratory Syncytial Virus (RSV) Challenge and Infection of Adults
Bindiya Bagga et al.
JOURNAL OF INFECTIOUS DISEASES (2015)
Secondhand Smoke Exposure and Illness Severity among Children Hospitalized with Pneumonia
Anna Ahn et al.
JOURNAL OF PEDIATRICS (2015)
Platelet and endothelial cell P-selectin are required for host defense against Klebsiella pneumoniae-induced pneumosepsis
S. . F. . De Stoppelaar et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2015)
Genetic Association Between CD143 rs4340 Polymorphism and Pneumonia risk A Meta Analysis
Hong Wang et al.
MEDICINE (2015)
The burgeoning family of unconventional T cells
Dale I. Godfrey et al.
NATURE IMMUNOLOGY (2015)
Respiratory epithelial cells orchestrate pulmonary innate immunity
Jeffrey A. Whitsett et al.
NATURE IMMUNOLOGY (2015)
Antiviral B cell and T cell immunity in the lungs
Christopher Chiu et al.
NATURE IMMUNOLOGY (2015)
Innate lymphoid cells in the initiation, regulation and resolution of inflammation
Gregory F. Sonnenberg et al.
NATURE MEDICINE (2015)
Community-Acquired Pneumonia Requiring Hospitalization among US Children
Seema Jain et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Community-Acquired Pneumonia Requiring Hospitalization among US Adults
S. Jain et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
TRPC6 channel translocation into phagosomal membrane augments phagosomal function
Vladimir Riazanski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Neutrophil trails guide influenza-specific CD8+ T cells in the airways
Kihong Lim et al.
SCIENCE (2015)
Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs
Georg Gasteiger et al.
SCIENCE (2015)
Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke
Odilo Engel et al.
STROKE (2015)
Application of a Neutral Community Model To Assess Structuring of the Human Lung Microbiome
Arvind Venkataraman et al.
MBIO (2015)
Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals
Christine M. Bassis et al.
MBIO (2015)
RSV-specific airway resident memory CD8+T cells and differential disease severity after experimental human infection
Agnieszka Jozwik et al.
NATURE COMMUNICATIONS (2015)
Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia
Norberto Gonzalez-Juarbe et al.
PLOS PATHOGENS (2015)
Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage
Kipyegon Kitur et al.
PLOS PATHOGENS (2015)
Respiratory Syncytial Virus Disease Is Mediated by Age-Variable IL-33
Jordy Saravia et al.
PLOS PATHOGENS (2015)
P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation
Dingxin Pan et al.
BLOOD (2015)
Effect of the adult pneumococcal polysaccharide vaccine on cardiovascular disease: a systematic review and meta-analysis
Shu Ren et al.
OPEN HEART (2015)
Childhood pneumonia increases risk for chronic obstructive pulmonary disease: the COPDGene study
Lystra P. Hayden et al.
RESPIRATORY RESEARCH (2015)
The Role of Surfactant in Lung Disease and Host Defense against Pulmonary Infections
SeungHye Han et al.
ANNALS OF THE AMERICAN THORACIC SOCIETY (2015)
Loss of caveolin-1 and adiponectin induces severe inflammatory lung injury following LPS challenge through excessive oxidative/nitrative stress
Lei Cai et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)
Diverse macrophage populations mediate acute lung inflammation and resolution
Neil R. Aggarwal et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)
Glutathione attenuates ethanol-induced alveolar macrophage oxidative stress and dysfunction by downregulating NADPH oxidases
Samantha M. Yeligar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)
Increased 1-Year Healthcare Use in Survivors of Severe Sepsis
Hallie C. Prescott et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
Foxa3 Induces Goblet Cell Metaplasia and Inhibits Innate Antiviral Immunity
Gang Chen et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
Risk of Cardiovascular Events in Survivors of Severe Sepsis
Sachin Yende et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
Roles of Lung Epithelium in Neutrophil Recruitment during Pneumococcal Pneumonia
Kazuko Yamamoto et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Resolution of Acute Inflammation in the Lung
Bruce D. Levy et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 76 (2014)
Antibiotic Treatment of Infections Due to Carbapenem-Resistant Enterobacteriaceae: Systematic Evaluation of the Available Evidence
Matthew E. Falagas et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice
Sacha F. de Stoppelaar et al.
BLOOD (2014)
Leukemia inhibitory factor protects the lung during respiratory syncytial viral infection
Robert F. Foronjy et al.
BMC IMMUNOLOGY (2014)
Identification, Characterization, and Natural Selection of Mutations Driving Airborne Transmission of A/H5N1 Virus
Martin Linster et al.
CELL (2014)
Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life
Joseph J. C. Thome et al.
CELL (2014)
Long-term Outcomes Following Development of New-Onset Atrial Fibrillation During Sepsis
Allan J. Walkey et al.
CHEST (2014)
Preventing Cardiovascular Complications of Acute Infection A Missed Opportunity?
Allan J. Walkey
CIRCULATION (2014)
Airway epithelial regulation of pulmonary immune homeostasis and inflammation
Teal S. Hallstrand et al.
CLINICAL IMMUNOLOGY (2014)
Two Decades of Mortality Trends Among Patients With Severe Sepsis: A Comparative Meta-Analysis
Elizabeth K. Stevenson et al.
CRITICAL CARE MEDICINE (2014)
Determinants of virulence of influenza A virus
E. J. A. Schrauwen et al.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2014)
Long-term risks after splenectomy among 8,149 cancer-free American veterans: a cohort study with up to 27 years follow-up
Sigurdur Y. Kristinsson et al.
HAEMATOLOGICA (2014)
CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection
Brian J. Laidlaw et al.
IMMUNITY (2014)
C-reactive protein is essential for innate resistance to pneumococcal infection
J. Paul Simons et al.
IMMUNOLOGY (2014)
Early Innate Immunity to Bacterial Infection in the Lung Is Regulated Systemically by the Commensal Microbiota via Nod-Like Receptor Ligands
Thomas B. Clarke
INFECTION AND IMMUNITY (2014)
Computational modeling of nanoscale and microscale particle deposition, retention and dosimetry in the mouse respiratory tract
B. Asgharian et al.
INHALATION TOXICOLOGY (2014)
Smoking and alcohol abuse are the most preventable risk factors for invasive pneumonia and other pneumococcal infections
Imma Grau et al.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2014)
Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure
Ashley G. Henderson et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Single-Molecule Long-Read 16S Sequencing To Characterize the Lung Microbiome from Mechanically Ventilated Patients with Suspected Pneumonia
Ian Toma et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2014)
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis
Georg F. Weber et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Cigarette Smoke Exposure Exacerbates Lung Inflammation and Compromises Immunity to Bacterial Infection
Amit A. Lugade et al.
JOURNAL OF IMMUNOLOGY (2014)
Conventional NK Cells Can Produce IL-22 and Promote Host Defense in Klebsiella pneumoniae Pneumonia
Xin Xu et al.
JOURNAL OF IMMUNOLOGY (2014)
Immunological Priming Requires Regulatory T Cells and IL-10-Producing Macrophages To Accelerate Resolution from Severe Lung Inflammation
Neil R. Aggarwal et al.
JOURNAL OF IMMUNOLOGY (2014)
Serial quantification of procalcitonin (PCT) predicts clinical outcome and prognosis in patients with community-acquired pneumonia (CAP)
Masaki Tamura et al.
JOURNAL OF INFECTION AND CHEMOTHERAPY (2014)
Resident Microbiota Affect Bordetella pertussis Infectious Dose and Host Specificity
Laura S. Weyrich et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
Activation of Type 3 Innate Lymphoid Cells and Interleukin 22 Secretion in the Lungs During Streptococcus pneumoniae Infection
Laurye Van Maele et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
Lung epithelial cells are essential effectors of inducible resistance to pneumonia
J. O. Cleaver et al.
MUCOSAL IMMUNOLOGY (2014)
Lung niches for the generation and maintenance of tissue-resident memory T cells
D. L. Turner et al.
MUCOSAL IMMUNOLOGY (2014)
The development and function of mucosal lymphoid tissues: a balancing act with micro-organisms
T. D. Randall et al.
MUCOSAL IMMUNOLOGY (2014)
Muc5b is required for airway defence
Michelle G. Roy et al.
NATURE (2014)
Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity
Kristin Westphalen et al.
NATURE (2014)
Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells
Giuliana Magri et al.
NATURE IMMUNOLOGY (2014)
Lung regeneration: mechanisms, applications and emerging stem cell populations
Darrell N. Kotton et al.
NATURE MEDICINE (2014)
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action
Julie Gibbs et al.
NATURE MEDICINE (2014)
Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo
David J. DiLillo et al.
NATURE MEDICINE (2014)
The co-pathogenesis of influenza viruses with bacteria in the lung
Jonathan A. McCullers
NATURE REVIEWS MICROBIOLOGY (2014)
Community-Acquired Pneumonia
Daniel M. Musher et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Multistate Point- Prevalence Survey of Health Care- Associated Infections
Shelley S. Magill et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
The Lung Microbiome of Ugandan HIV-Infected Pneumonia Patients Is Compositionally and Functionally Distinct from That of San Franciscan Patients
Shoko Iwai et al.
PLOS ONE (2014)
No Impairment in Host Defense against Streptococcus pneumoniae in Obese CPEfat/fat Mice
Peter Mancuso et al.
PLOS ONE (2014)
Neuroendocrine regulation of inflammation
Caroline J. Padro et al.
SEMINARS IN IMMUNOLOGY (2014)
Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac Function
Armand O. Brown et al.
PLOS PATHOGENS (2014)
Alcohol Induced Mitochondrial Oxidative Stress and Alveolar Macrophage Dysfunction
Yan Liang et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands
Victoria Y. Alfaro et al.
FRONTIERS IN PHARMACOLOGY (2014)
Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease
Lydia Finney et al.
LANCET RESPIRATORY MEDICINE (2014)
Effects of intra-abdominal sepsis on atherosclerosis in mice
Ata Murat Kaynar et al.
CRITICAL CARE (2014)
Human memory T cells: generation, compartmentalization and homeostasis
Donna L. Farber et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Alveolar macrophages: plasticity in a tissue-specific context
Tracy Hussell et al.
NATURE REVIEWS IMMUNOLOGY (2014)
IL-22 Is Essential for Lung Epithelial Repair following Influenza Infection
Derek A. Pociask et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury
Rachel L. Zemans et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Heterogeneity of lung mononuclear phagocytes during pneumonia: contribution of chemokine receptors
Lanlin Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Bidirectional Relationship between Cognitive Function and Pneumonia
Faraaz Ali Shah et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
CXCL10-CXCR3 Enhances the Development of Neutrophil-mediated Fulminant Lung Injury of Viral and Nonviral Origin
Akihiko Ichikawa et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Outgrowth of the Bacterial Airway Microbiome after Rhinovirus Exacerbation of Chronic Obstructive Pulmonary Disease
Philip L. Molyneaux et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Primary Ciliary Dyskinesia Recent Advances in Diagnostics, Genetics, and Characterization of Clinical Disease
Michael R. Knowles et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Alcoholism Causes Alveolar Macrophage Zinc Deficiency and Immune Dysfunction
Ashish J. Mehta et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Toll-Like Receptor-2/6 and Toll-Like Receptor-9 Agonists Suppress Viral Replication but Not Airway Hyperreactivity in Guinea Pigs
Matthew G. Drake et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)
Lower respiratory tract infection in the first year of life is associated with worse lung function in adult life: prospective results from the Barry Caerphilly Growth study
James A. Lopez Bernal et al.
ANNALS OF EPIDEMIOLOGY (2013)
T Cell-Mediated Host Immune Defenses in the Lung
Kong Chen et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)
Regulation and Repair of the Alveolar-Capillary Barrier in Acute Lung Injury
Jahar Bhattacharya et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 75 (2013)
Breastfeeding for reducing the risk of pneumonia morbidity and mortality in children under two: a systematic literature review and meta-analysis
Laura M. Lamberti et al.
BMC PUBLIC HEALTH (2013)
A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection
Marlene Brandes et al.
CELL (2013)
Serotype-independent pneumococcal vaccines
Eliane Namie Miyaji et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
Alveolar macrophages in pulmonary host defence - the unrecognized role of apoptosis as a mechanism of intracellular bacterial killing
J. D. Aberdein et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2013)
Long-term Survival Following Pneumococcal Pneumonia
Barcleigh Sandvall et al.
CLINICAL INFECTIOUS DISEASES (2013)
Invasive pneumococcal disease in patients with an underlying pulmonary disorder
M. Inghammar et al.
CLINICAL MICROBIOLOGY AND INFECTION (2013)
Benzodiazepine Versus Nonbenzodiazepine-Based Sedation for Mechanically Ventilated, Critically Ill Adults: A Systematic Review and Meta-Analysis of Randomized Trials
Gilles L. Fraser et al.
CRITICAL CARE MEDICINE (2013)
Risk factors for severe acute lower respiratory infections in children - a systematic review and meta-analysis
Stewart Jackson et al.
CROATIAN MEDICAL JOURNAL (2013)
The impact of viral genotype on pathogenesis and disease severity: respiratory syncytial virus and human rhinoviruses
Martin L. Moore et al.
CURRENT OPINION IN IMMUNOLOGY (2013)
Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets
Taheri Sathaliyawala et al.
IMMUNITY (2013)
Multipronged CD4+ T-cell effector and memory responses cooperate to provide potent immunity against respiratory virus
Tara M. Strutt et al.
IMMUNOLOGICAL REVIEWS (2013)
Roles of STAT3 in Protein Secretion Pathways during the Acute-Phase Response
Ayele-Nati N. Ahyi et al.
INFECTION AND IMMUNITY (2013)
Viral-bacterial interactions-therapeutic implications
Jane C. Deng
INFLUENZA AND OTHER RESPIRATORY VIRUSES (2013)
Bacterial and viral infections associated with influenza
Carol Joseph et al.
INFLUENZA AND OTHER RESPIRATORY VIRUSES (2013)
Association Between Influenza Vaccination and Cardiovascular Outcomes in High-Risk Patients A Meta-analysis
Jacob A. Udell et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)
Diagnoses and Timing of 30-Day Readmissions After Hospitalization for Heart Failure, Acute Myocardial Infarction, or Pneumonia
Kumar Dharmarajan et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)
Innate Stat3-mediated induction of the antimicrobial protein Reg3γ is required for host defense against MRSA pneumonia
Sun-Mi Choi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
Martin Guilliams et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Increased Susceptibility to Pulmonary Pseudomonas Infection in Splunc1 Knockout Mice
Yanyan Liu et al.
JOURNAL OF IMMUNOLOGY (2013)
Monocyte- and Macrophage-Targeted NADPH Oxidase Mediates Antifungal Host Defense and Regulation of Acute Inflammation in Mice
Melissa J. Grimm et al.
JOURNAL OF IMMUNOLOGY (2013)
Interleukin-22 Reduces Lung Inflammation during Influenza A Virus Infection and Protects against Secondary Bacterial Infection
Stoyan Ivanov et al.
JOURNAL OF VIROLOGY (2013)
Acute pneumonia and the cardiovascular system
Vicente F. Corrales-Medina et al.
LANCET (2013)
Ending of preventable deaths from pneumonia and diarrhoea: an achievable goal
Mickey Chopra et al.
LANCET (2013)
STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with relevance in resolution of bacterial pneumonia
S. L. Poe et al.
MUCOSAL IMMUNOLOGY (2013)
IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection
P. Kumar et al.
MUCOSAL IMMUNOLOGY (2013)
Cellular immune correlates of protection against symptomatic pandemic influenza
Saranya Sridhar et al.
NATURE MEDICINE (2013)
Post-Hospital Syndrome - An Acquired, Transient Condition of Generalized Risk
Harlan M. Krumholz
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection
Hai-Nv Gao et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
US Hospitalizations for Pneumonia after a Decade of Pneumococcal Vaccination
Marie R. Griffin et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Long-Term Cognitive Impairment after Critical Illness
P. P. Pandharipande et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Severe Sepsis and Septic Shock REPLY
Derek C. Angus et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Body mass index and risk of pneumonia: a systematic review and meta-analysis
D. T. Phung et al.
OBESITY REVIEWS (2013)
Vitamin D Status and Community-Acquired Pneumonia: Results from the Third National Health and Nutrition Examination Survey
Sadeq A. Quraishi et al.
PLOS ONE (2013)
Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase
Danny Jonigk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Neutrophils in innate and adaptive immunity
Sebastien Jaillon et al.
SEMINARS IN IMMUNOPATHOLOGY (2013)
T helper 17 cells are involved in the local and systemic inflammatory response in community-acquired pneumonia
Marthe S. Paats et al.
THORAX (2013)
Risk factors for community-acquired pneumonia in adults in Europe: a literature review
Antoni Torres et al.
THORAX (2013)
Influence of bacterial interactions on pneumococcal colonization of the nasopharynx
Joshua R. Shakl et al.
TRENDS IN MICROBIOLOGY (2013)
The intestinal microbiota and host immune interactions in the critically ill
Tim J. Schuijt et al.
TRENDS IN MICROBIOLOGY (2013)
Lack of cross-protection against invasive pneumonia caused by heterologous strains following murine Streptococcus pneumoniae nasopharyngeal colonisation despite whole cell ELISAs showing significant cross-reactive IgG
Jonathan M. Cohen et al.
VACCINE (2013)
Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages
Jian Wang et al.
NATURE COMMUNICATIONS (2013)
Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung
Adam K. A. Wright et al.
PLOS PATHOGENS (2013)
Health Care-Associated Infections A Meta-analysis of Costs and Financial Impact on the US Health Care System
Eyal Zimlichman et al.
JAMA INTERNAL MEDICINE (2013)
Neutrophil recruitment and function in health and inflammation
Elzbieta Kolaczkowska et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions
Patrick J. Brennan et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Innate lymphoid cells - how did we miss them?
Jennifer A. Walker et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Innate lymphoid cells - a proposal for uniform nomenclature
Hergen Spits et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Severe Sepsis and Septic Shock
Derek C. Angus et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TLR4-dependent GM-CSF protects against lung injury in Gram-negative bacterial pneumonia
Louis R. Standiford et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
Respiratory Infection and the Impact of Pulmonary Immunity on Lung Health and Disease
Joseph P. Mizgerd
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Depressive Symptoms and Impaired Physical Function after Acute Lung Injury A 2-Year Longitudinal Study
Oscar J. Bienvenu et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
The Relationship between Lung Inflammation and Cardiovascular Disease
Stephan Van Eeden et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Pulmonary Macrophage Subpopulations in the Induction and Resolution of Acute Lung Injury
Laura K. Johnston et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Clinical Features of Patients With Recurrent Invasive Streptococcus pneumoniae Disease
Maurice A. Mufson et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2012)
Alcohol Abuse, the Alveolar Macrophage and Pneumonia
Ashish J. Mehta et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2012)
Clinical effectiveness of pneumococcal vaccination against acute myocardial infarction and stroke in people over 60 years: the CAPAMIS study, one-year follow-up
Angel Vila-Corcoles et al.
BMC PUBLIC HEALTH (2012)
Evaluation of Risk Factors for Severe Pneumonia in Children: The Pneumonia Etiology Research for Child Health Study
Chizoba B. Wonodi et al.
CLINICAL INFECTIOUS DISEASES (2012)
Rehabilitation of mind and body after intensive care unit discharge: A step closer to recovery
Dale M. Needham et al.
CRITICAL CARE MEDICINE (2012)
Acute lung injury in critical neurological illness
Robert E. Hoesch et al.
CRITICAL CARE MEDICINE (2012)
Improving long-term outcomes after discharge from intensive care unit: Report from a stakeholders' conference
Dale M. Needham et al.
CRITICAL CARE MEDICINE (2012)
New respiratory viral infections
Tuomas Jartti et al.
CURRENT OPINION IN PULMONARY MEDICINE (2012)
Age-related changes in phagocytic activity and production of pro-inflammatory cytokines by lipopolysaccharide stimulated porcine alveolar macrophages
Mohammad Ariful Islam et al.
CYTOKINE (2012)
Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia
Martina Weber et al.
FASEB JOURNAL (2012)
Innate Immune Function by Toll-like Receptors: Distinct Responses in Newborns and the Elderly
Tobias R. Kollmann et al.
IMMUNITY (2012)
Interleukin-1β Regulates CXCL8 Release and Influences Disease Outcome in Response to Streptococcus pneumoniae, Defining Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages
Helen M. Marriott et al.
INFECTION AND IMMUNITY (2012)
Alveolar Macrophages in Neonatal Mice Are Inherently Unresponsive to Pneumocystis murina Infection
Cathryn Kurkjian et al.
INFECTION AND IMMUNITY (2012)
Prevention of lung injury by Muc1 mucin in a mouse model of repetitive Pseudomonas aeruginosa infection
Tsuyoshi Umehara et al.
INFLAMMATION RESEARCH (2012)
Acute Respiratory Distress Syndrome The Berlin Definition
V. Marco Ranieri et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)
Association of Diagnostic Coding With Trends in Hospitalizations and Mortality of Patients With Pneumonia, 2003-2009
Peter K. Lindenauer et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)
Interleukin-22 Is Produced by Invariant Natural Killer T Lymphocytes during Influenza A Virus Infection POTENTIAL ROLE IN PROTECTION AGAINST LUNG EPITHELIAL DAMAGES
Christophe Paget et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice
Lee J. Quinton et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice
Kathrin Steinwede et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Adiponectin Attenuates Lipopolysaccharide-Induced Acute Lung Injury through Suppression of Endothelial Cell Activation
Jason M. Konter et al.
JOURNAL OF IMMUNOLOGY (2012)
Ablation of Leptin Receptor-Mediated ERK Activation Impairs Host Defense against Gram-Negative Pneumonia
Peter Mancuso et al.
JOURNAL OF IMMUNOLOGY (2012)
Leukemia Inhibitory Factor Signaling Is Required for Lung Protection during Pneumonia
Lee J. Quinton et al.
JOURNAL OF IMMUNOLOGY (2012)
Type I Alveolar Epithelial Cells Mount Innate Immune Responses during Pneumococcal Pneumonia
Kazuko Yamamoto et al.
JOURNAL OF IMMUNOLOGY (2012)
Intrapulmonary G-CSF Rescues Neutrophil Recruitment to the Lung and Neutrophil Release to Blood in Gram-Negative Bacterial Infection in MCP-1-/- Mice
Gayathriy Balamayooran et al.
JOURNAL OF IMMUNOLOGY (2012)
Clinical and Economic Burden of Community-Acquired Pneumonia in the Medicare Fee-for-Service Population
Holly Yu et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2012)
Population Burden of Long-Term Survivorship After Severe Sepsis in Older Americans
Theodore J. Iwashyna et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2012)
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
Christopher J. L. Murray et al.
LANCET (2012)
Effect of Aging on Cough and Swallowing Reflexes: Implications for Preventing Aspiration Pneumonia
Satoru Ebihara et al.
LUNG (2012)
B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
Irene Puga et al.
NATURE IMMUNOLOGY (2012)
Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans
Tom M. Wilkinson et al.
NATURE MEDICINE (2012)
Innate and adaptive immune responses in asthma
Stephen T. Holgate
NATURE MEDICINE (2012)
Iron metabolism and the innate immune response to infection
Erin E. Johnson et al.
MICROBES AND INFECTION (2012)
A Tale of Coronary Artery Disease and Myocardial Infarction
Elizabeth G. Nabel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Long Term Sequelae from Childhood Pneumonia; Systematic Review and Meta-Analysis
Karen Edmond et al.
PLOS ONE (2012)
Poly I:C Enhances Susceptibility to Secondary Pulmonary Infections by Gram-Positive Bacteria
Xiaoli Tian et al.
PLOS ONE (2012)
SAM-pointed domain ETS factor mediates epithelial cell-intrinsic innate immune signaling during airway mucous metaplasia
Thomas R. Korfhagen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors
Tara M. Strutt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Role of epithelial mucins during airway infection
Kwang Chul Kim
PULMONARY PHARMACOLOGY & THERAPEUTICS (2012)
Characterization of Th17 responses to Streptococcus pneumoniae in humans: Comparisons between adults and children in a developed and a developing country
Anna Lundgren et al.
VACCINE (2012)
Interaction of Lipocalin 2, Transferrin, and Siderophores Determines the Replicative Niche of Klebsiella pneumoniae during Pneumonia
Michael A. Bachman et al.
MBIO (2012)
Regulating the adaptive immune response to respiratory virus infection
Thomas J. Braciale et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Expanding roles for CD4+ T cells in immunity to viruses
Susan L. Swain et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Exudate Macrophages Attenuate Lung Injury by the Release of IL-1 Receptor Antagonist in Gram-negative Pneumonia
Susanne Herold et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Fas Determines Differential Fates of Resident and Recruited Macrophages during Resolution of Acute Lung Injury
William J. Janssen et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Interferon-γ Production by Neutrophils during Bacterial Pneumonia in Mice
Mitsuhiro Yamada et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Earliest Innate Immune Responses Require Macrophage RelA during Pneumococcal Pneumonia
Lynnelle A. Pittet et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment
Michael A. Matthay et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)
Doubts concerning the recently reported human neutrophil lifespan of 5.4 days
Paul S. Tofts et al.
BLOOD (2011)
Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection
Pooja A. Kumar et al.
CELL (2011)
NF-kappa B and STAT3 signaling hubs for lung innate immunity
Lee J. Quinton et al.
CELL AND TISSUE RESEARCH (2011)
Immune Dysfunction and Infections in Patients With Cirrhosis
Alexander R. Bonnel et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2011)
Th17 Cells Mediate Clade-Specific, Serotype-Independent Mucosal Immunity
Kong Chen et al.
IMMUNITY (2011)
Cathepsin G and Neutrophil Elastase Play Critical and Nonredundant Roles in Lung-Protective Immunity against Streptococcus pneumoniae in Mice
Ines Hahn et al.
INFECTION AND IMMUNITY (2011)
Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1-and IL-23-Dependent Manner during Invasive Fungal Infection
Jessica L. Werner et al.
INFECTION AND IMMUNITY (2011)
Incident Stroke and Mortality Associated With New-Onset Atrial Fibrillation in Patients Hospitalized With Severe Sepsis
Allan J. Walkey et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)
Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure
Jonathan S. Boomer et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection
Jens Wrammert et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection
Manfred Brigl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
FoxM1 mediates the progenitor function of type II epithelial cells in repairing alveolar injury induced by Pseudomonas aeruginosa
Yuru Liu et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Disruption of Leptin Receptor-STAT3 Signaling Enhances Leukotriene Production and Pulmonary Host Defense against Pneumococcal Pneumonia
Peter Mancuso et al.
JOURNAL OF IMMUNOLOGY (2011)
Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection
John R. Teijaro et al.
JOURNAL OF IMMUNOLOGY (2011)
Airway Epithelial MyD88 Restores Control of Pseudomonas aeruginosa Murine Infection via an IL-1-Dependent Pathway
Lilia A. Mijares et al.
JOURNAL OF IMMUNOLOGY (2011)
Alcohol Suppresses the Granulopoietic Response to Pulmonary Streptococcus pneumoniae Infection with Enhancement of STAT3 Signaling
Robert W. Siggins et al.
JOURNAL OF IMMUNOLOGY (2011)
Nonhematopoietic Cells Are Key Players in Innate Control of Bacterial Airway Infection
Salome LeibundGut-Landmann et al.
JOURNAL OF IMMUNOLOGY (2011)
Synergistic Interactions of TLR2/6 and TLR9 Induce a High Level of Resistance to Lung Infection in Mice
Jeffrey M. Duggan et al.
JOURNAL OF IMMUNOLOGY (2011)
Opioid Drug Abuse and Modulation of Immune Function: Consequences in the Susceptibility to Opportunistic Infections
Sabita Roy et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2011)
Differential effects of kidney-lung cross-talk during acute kidney injury and bacterial pneumonia
Kai Singbartl et al.
KIDNEY INTERNATIONAL (2011)
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
Laurel A. Monticelli et al.
NATURE IMMUNOLOGY (2011)
Functional Disability 5 Years after Acute Respiratory Distress Syndrome
Margaret S. Herridge et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Analysis of the Lung Microbiome in the Healthy Smoker and in COPD
John R. Erb-Downward et al.
PLOS ONE (2011)
Resident Memory T Cells (TRM) Are Abundant in Human Lung: Diversity, Function, and Antigen Specificity
Rahul Purwar et al.
PLOS ONE (2011)
The Natural Cytotoxicity Receptor 1 Contribution to Early Clearance of Streptococcus pneumoniae and to Natural Killer-Macrophage Cross Talk
Shirin Elhaik-Goldman et al.
PLOS ONE (2011)
Elevated Hemostasis Markers after Pneumonia Increases One-Year Risk of All-Cause and Cardiovascular Deaths
Sachin Yende et al.
PLOS ONE (2011)
Neutrophil transmigration triggers repair of the lung epithelium via β-catenin signaling
Rachel L. Zemans et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Microbiota regulates immune defense against respiratory tract influenza A virus infection
Takeshi Ichinohe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
EPIDERMAL GROWTH FACTOR IMPROVES SURVIVAL AND PREVENTS INTESTINAL INJURY IN A MURINE MODEL OF PSEUDOMONAS AERUGINOSA PNEUMONIA
Jessica A. Dominguez et al.
SHOCK (2011)
Regulation of Inflammation by Short Chain Fatty Acids
Marco A. R. Vinolo et al.
NUTRIENTS (2011)
Autocrine Regulation of Pulmonary Inflammation by Effector T-Cell Derived IL-10 during Infection with Respiratory Syncytial Virus
Jie Sun et al.
PLOS PATHOGENS (2011)
A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci
Martin A. Bewley et al.
PLOS PATHOGENS (2011)
The double life of a B-1 cell: self-reactivity selects for protective effector functions
Nicole Baumgarth
NATURE REVIEWS IMMUNOLOGY (2011)
TLR4 signalling in pulmonary stromal cells is critical for inflammation and immunity in the airways
Frederic Perros et al.
RESPIRATORY RESEARCH (2011)
Long-Term Exposure to Ambient Air Pollution and Risk of Hospitalization with Community-acquired Pneumonia in Older Adults
Binod Neupane et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)
Stimulated Innate Resistance of Lung Epithelium Protects Mice Broadly against Bacteria and Fungi
Scott E. Evans et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2010)
Survivorship Will Be the Defining Challenge of Critical Care in the 21st Century
Theodore J. Iwashyna
ANNALS OF INTERNAL MEDICINE (2010)
Inducible Innate Resistance of Lung Epithelium to Infection
Scott E. Evans et al.
ANNUAL REVIEW OF PHYSIOLOGY (2010)
In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days
Janesh Pillay et al.
BLOOD (2010)
Myeloid RelA regulates pulmonary host defense networks
C. Hess et al.
EUROPEAN RESPIRATORY JOURNAL (2010)
Obesity and risk of subsequent hospitalisation with pneumonia
J. B. Kornum et al.
EUROPEAN RESPIRATORY JOURNAL (2010)
Infection as a comorbidity of COPD
S. Sethi
EUROPEAN RESPIRATORY JOURNAL (2010)
CXCL5 Regulates Chemokine Scavenging and Pulmonary Host Defense to Bacterial Infection
Junjie Mei et al.
IMMUNITY (2010)
Importance of CXC Chemokine Receptor 2 in Alveolar Neutrophil and Exudate Macrophage Recruitment in Response to Pneumococcal Lung Infection
Wiebke Herbold et al.
INFECTION AND IMMUNITY (2010)
Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis
Theodore J. Iwashyna et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow
Kyle J. Eash et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function
Leif E. Sander et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Requisite Role of the Cholinergic alpha 7 Nicotinic Acetylcholine Receptor Pathway in Suppressing Gram-Negative Sepsis-Induced Acute Lung Inflammatory Injury
Xiao Su et al.
JOURNAL OF IMMUNOLOGY (2010)
Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung
Cherrie-Lee Small et al.
JOURNAL OF IMMUNOLOGY (2010)
CXCL1 Regulates Pulmonary Host Defense to Klebsiella Infection via CXCL2, CXCL5, NF-κB, and MAPKs
Shanshan Cai et al.
JOURNAL OF IMMUNOLOGY (2010)
Assessment of Seasonal Influenza A Virus-Specific CD4 T-Cell Responses to 2009 Pandemic H1N1 Swine-Origin Influenza A Virus
Xinhui Ge et al.
JOURNAL OF VIROLOGY (2010)
Memory CD4+ T cells induce innate responses independently of pathogen
Tara M. Strutt et al.
NATURE MEDICINE (2010)
Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity
Thomas B. Clarke et al.
NATURE MEDICINE (2010)
MEDICAL PROGRESS Airway Mucus Function and Dysfunction
John V. Fahy et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Low zinc status: a new risk factor for pneumonia in the elderly?
Junaidah B. Barnett et al.
NUTRITION REVIEWS (2010)
Disordered Microbial Communities in Asthmatic Airways
Markus Hilty et al.
PLOS ONE (2010)
Burden of Community-Acquired Pneumonia in North American Adults
Thomas M. File et al.
POSTGRADUATE MEDICINE (2010)
Association of Secondhand Smoke Exposure with Pediatric Invasive Bacterial Disease and Bacterial Carriage: A Systematic Review and Meta-analysis
Chien-Chang Lee et al.
PLOS MEDICINE (2010)
Research Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial
Pratik P. Pandharipande et al.
CRITICAL CARE (2010)
Amicus or Adversary Platelets in Lung Biology, Acute Injury, and Inflammation
Fernando A. Bozza et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)
Disruption of iron homeostasis and lung disease
Andrew J. Ghio
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions
Kyle J. Eash et al.
BLOOD (2009)
Pulmonary alveolar proteinosis, a primary immunodeficiency of impaired GM-CSF stimulation of macrophages
Bruce C. Trapnell et al.
CURRENT OPINION IN IMMUNOLOGY (2009)
Neutrophil Recruitment to the Lungs during Bacterial Pneumonia
Ann Craig et al.
INFECTION AND IMMUNITY (2009)
Mechanisms of the Hepatic Acute-Phase Response during Bacterial Pneumonia
Lee J. Quinton et al.
INFECTION AND IMMUNITY (2009)
International Study of the Prevalence and Outcomes of Infection in Intensive Care Units
Jean-Louis Vincent et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production
Gang Chen et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury
Franco R. D'Alessio et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice
Arash Shahangian et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Important Role for CC Chemokine Ligand 2-Dependent Lung Mononuclear Phagocyte Recruitment to Inhibit Sepsis in Mice Infected with Streptococcus pneumoniae
Christine Winter et al.
JOURNAL OF IMMUNOLOGY (2009)
Lipocalin 2 Is Required for Pulmonary Host Defense against Klebsiella Infection
Yvonne R. Chan et al.
JOURNAL OF IMMUNOLOGY (2009)
Tc17, a Unique Subset of CD8 T Cells That Can Protect against Lethal Influenza Challenge
Hiromasa Hamada et al.
JOURNAL OF IMMUNOLOGY (2009)
Age-Associated Inflammation and Toll-Like Receptor Dysfunction Prime the Lungs for Pneumococcal Pneumonia
Ernesto Hinojosa et al.
JOURNAL OF INFECTIOUS DISEASES (2009)
Micronutrient Deficiencies Are Associated with Impaired Immune Response and Higher Burden of Respiratory Infections in Elderly Ecuadorians
Davidson H. Hamer et al.
JOURNAL OF NUTRITION (2009)
Pathogenesis, treatment, and prevention of pneumococcal pneumonia
Tom van der Poll et al.
LANCET (2009)
Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10
Jie Sun et al.
NATURE MEDICINE (2009)
Decontamination of the Digestive Tract and Oropharynx in ICU Patients
A. M. G. A. de Smet et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Historical Perspective - Emergence of Influenza A (H1N1) Viruses
Shanta M. Zimmer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Intensive versus Conventional Glucose Control in Critically Ill Patients
S. Finfer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Upregulation of Phagocyte-Derived Catecholamines Augments the Acute Inflammatory Response
Michael A. Flierl et al.
PLOS ONE (2009)
Pseudomonas aeruginosa LPS or Flagellin Are Sufficient to Activate TLR-Dependent Signaling in Murine Alveolar Macrophages and Airway Epithelial Cells
Eloise Raoust et al.
PLOS ONE (2009)
The Alphabet Soup of Pneumonia: CAP, HAP, HCAP, NHAP, and VAP
Nitin Anand et al.
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2009)
THE SYSTEMIC AND PULMONARY LPS BINDING PROTEIN RESPONSE TO INTRATRACHEAL LIPOPOLYSACCHARIDE
Lisa Gamble et al.
SHOCK (2009)
New perspectives on community-acquired pneumonia in 388 406 patients. Results from a nationwide mandatory performance measurement programme in healthcare quality
S. Ewig et al.
THORAX (2009)
Bench-to-bedside review: Delirium in ICU patients - importance of sleep deprivation
Gerald L. Weinhouse et al.
CRITICAL CARE (2009)
Bench-to-bedside review: Mobilizing patients in the intensive care unit - from pathophysiology to clinical trials
Alex D. Truong et al.
CRITICAL CARE (2009)
How cigarette smoke skews immune responses to promote infection, lung disease and cancer
Martin R. Staempfli et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Incidence and significance of a positive troponin test in bacteremic patients without acute coronary syndrome
Carmel Kalla et al.
AMERICAN JOURNAL OF MEDICINE (2008)
GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium
Hiroshi Kida et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Apoptosis in the lung: induction, clearance and detection
P. M. Henson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice
Cecilia G. Clement et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)
Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis
Sachin Yende et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)
Alveolar epithelial STAT3, IL-6 family cytokines, and host defense during Escherichia coli pneumonia
Lee J. Quinton et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)
The prolonged life-span of alveolar macrophages
Jaime Murphy et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)
Epidemiology and etiology of childhood pneumonia
Igor Rudan et al.
BULLETIN OF THE WORLD HEALTH ORGANIZATION (2008)
The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection
S. M. Chen et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2008)
Granulocyte colony-stimulating factor: Molecular mechanisms of action during steady state and 'emergency' hematopoiesis
Athanasia D. Panopoulos et al.
CYTOKINE (2008)
STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury
Machiko Ikegami et al.
JOURNAL OF APPLIED PHYSIOLOGY (2008)
Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection
Arnaud Didierlaurent et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
NK cells play a critical protective role in host defense against acute extracellular Staphylococcus aureus bacterial infection in the lung
Cherrie-Lee Small et al.
JOURNAL OF IMMUNOLOGY (2008)
Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: Implications for pandemic influenza preparedness
David M. Morens et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
Neutrophil Depletion Causes a Fatal Defect in Murine Pulmonary Staphylococcus aureus clearance
Charles M. Robertson et al.
JOURNAL OF SURGICAL RESEARCH (2008)
Interaction of SIGNR1 expressed by marginal zone macrophages with marginal zone B cells is essential to early IgM responses against Streptococcus pneumoniae
Estella A. Koppel et al.
MOLECULAR IMMUNOLOGY (2008)
Structural recognition and functional activation of FcγR by innate pentraxins
Jinghua Lu et al.
NATURE (2008)
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
Shean J. Aujla et al.
NATURE MEDICINE (2008)
Update on Avian Influenza A (H5N1) Virus Infection in Humans
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Pyogenic bacterial infections in humans with MyD88 deficiency
Horst von Bernuth et al.
SCIENCE (2008)
The impact of vaccines on pneumonia:: Key lessons from Haemophilus influenzae type b conjugate vaccines
Bradford D. Gessner et al.
VACCINE (2008)
Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies
Carmen Giefing et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Activation of the signal transducers and activators of the transcription 3 pathway in alveolar epithelial cells induces inflammation and adenocarcinomas in mouse lung
Yuan Li et al.
CANCER RESEARCH (2007)
Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae
Jose Yuste et al.
PLOS PATHOGENS (2007)
Mechanisms of sepsis-induced cardiac dysfunction
Alain Rudiger et al.
CRITICAL CARE MEDICINE (2007)
Airway epithelium controls lung inflammation and injury through the NF-κB pathway
Dong-sheng Cheng et al.
JOURNAL OF IMMUNOLOGY (2007)
Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host Defense to Streptococcus pneumoniae infection in mice:: Role of the CCL2-CCR2 axis
Christine Winter et al.
JOURNAL OF IMMUNOLOGY (2007)
Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection
Alyssa D. Gregory et al.
BLOOD (2007)
The 1918 influenza pandemic: Insights for the 21st century
David M. Morens et al.
JOURNAL OF INFECTIOUS DISEASES (2007)
Prevalence, serotypes, and risk factors for pneumococcal carriage among HIV-infected adults
Christiane Nicoletti et al.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2007)
Accumulation of gamma/delta T cells in the lungs and their roles in neutrophil-mediated host defense against pneumococcal infection
Chikara Nakasone et al.
MICROBES AND INFECTION (2007)
Functions and regulation of NF-κB RelA during pneumococcal pneumonia
Lee J. Quinton et al.
JOURNAL OF IMMUNOLOGY (2007)
Redundant Toll-like receptor signaling in the pulmonary host response to Pseudomonas aeruginosa
Shawn J. Skerrett et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Glutathione availability modulates alveolar macrophage function in the chronic ethanol-fed rat
Lou Ann S. Brown et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Common infections in diabetes: pathogenesis, management and relationship to glycaemic control
Anton Y. Peleg et al.
DIABETES-METABOLISM RESEARCH AND REVIEWS (2007)
CFTR regulates phagosome acidification in macrophages and alters bactericidal activity
Anke Di et al.
NATURE CELL BIOLOGY (2006)
Stat3 is required for cytoprotection of the respiratory epithelium during adenoviral infection
Yohei Matsuzaki et al.
JOURNAL OF IMMUNOLOGY (2006)
An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps
K Beiter et al.
CURRENT BIOLOGY (2006)
Roles of interleukin-6 in activation of STAT proteins and recruitment of neutrophils during Escherichia coli pneumonia
MR Jones et al.
JOURNAL OF INFECTIOUS DISEASES (2006)
The acute-phase response and serum amyloid a inhibit the inflammatory response to Acinetobacter baumannii pneumonia
R Renckens et al.
JOURNAL OF INFECTIOUS DISEASES (2006)
Trends in hospitalizations for pneumonia among persons aged 65 years or older in the United States, 1988-2002
AM Fry et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
Pneumonia-induced sepsis and gut injury:: Effects of a poly-(ADP-ribose) polymerase inhibitor
SM Lobo et al.
JOURNAL OF SURGICAL RESEARCH (2005)
Lung NF-κB activation and neutrophil recruitment require IL-1 and TNF receptor signaling during pneumococcal pneumonia
MR Jones et al.
JOURNAL OF IMMUNOLOGY (2005)
Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin
N Noulin et al.
JOURNAL OF IMMUNOLOGY (2005)
G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow
CL Semerad et al.
BLOOD (2005)
An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia
AM Hajjar et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2005)
Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice
B Albiger et al.
CELLULAR MICROBIOLOGY (2005)
Structure and function of the spleen
RE Mebius et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Overexpression of Stat3C in pulmonary epithelium protects against hyperoxic lung injury
XM Lian et al.
JOURNAL OF IMMUNOLOGY (2005)
Induction of CXCL5 during inflammation in the rodent lung involves activation of alveolar epithelium
S Jeyaseelan et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2005)
Repeated stimulation of CD4 effector T cells can limit their protective function
DM Jelley-Gibbs et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Febrile-range hyperthermia augments neutrophil accumulation and enhances lung injury in experimental gram-negative bacterial pneumonia
P Rice et al.
JOURNAL OF IMMUNOLOGY (2005)
Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance
HM Marriott et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Protein chip array profiling analysis in patients with severe acute respiratory syndrome identified serum amyloid a protein as a biomarker potentially useful in monitoring the extent of pneumonia
TTC Yip et al.
CLINICAL CHEMISTRY (2005)
Activation of neutrophils and inhibition of the proinflammatory cytokine response by endogenous granulocyte colony-stimulating factor in murine pneumococcal pneumonia
S Knapp et al.
JOURNAL OF INFECTIOUS DISEASES (2004)
Contribution of C-reactive protein to the diagnosis and assessment of severity of community-acquired pneumonia
J Almirall et al.
CHEST (2004)
Escherichia coli pneumonia enhances granulopoiesis and the mobilization of myeloid progenitor cells into the systemic circulation
LM Shahbazian et al.
CRITICAL CARE MEDICINE (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
TH Flo et al.
NATURE (2004)
Role of the CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis
BT Suratt et al.
BLOOD (2004)
Mannose-binding lectin gene polymorphism is a modulating factor in repeated respiratory infections
K Gomi et al.
CHEST (2004)
The metabolic syndrome, inflammation, and risk of cognitive decline
K Yaffe et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)
LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia
J Branger et al.
INTERNATIONAL IMMUNOLOGY (2004)
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
E Nemeth et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Use of a broader determinants of health model for community-acquired pneumonia in seniors
MB Loeb
CLINICAL INFECTIOUS DISEASES (2004)
Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection
DH Dockrell et al.
JOURNAL OF IMMUNOLOGY (2003)
The influence of uraemia and haemodialysis on neutrophil phagocytosis and antimicrobial killing
K Anding et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2003)
Inflammatory markers and cognition in well-functioning African-American and white elders
K Yaffe et al.
NEUROLOGY (2003)
Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest
CM Coopersmith et al.
CRITICAL CARE MEDICINE (2003)
Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation:: Role of the CCL2-CCR2 axis
UA Maus et al.
JOURNAL OF IMMUNOLOGY (2003)
CCL20 is an inducible product of human airway epithelia with innate immune properties
TD Starner et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2003)
BCL-2 inhibits gut epithelial apoptosis induced by acute lung injury in mice but has no effect on survival
KD Husain et al.
SHOCK (2003)
Human natural killer cell deficiencies and susceptibility to infection
JS Orange
MICROBES AND INFECTION (2002)
G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood
CL Semerad et al.
IMMUNITY (2002)
The role of CC chemokine receptor 2 in alveolar monocyte and neutrophil immigration in intact mice
U Maus et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)
The granulocyte colony-stimulating factor response after intrapulmonary and systemic bacterial challenges
LJ Quinton et al.
JOURNAL OF INFECTIOUS DISEASES (2002)
Causes of death for patients with community-acquired pneumonia - Results from the pneumonia patient outcomes research team cohort study
EM Mortensen et al.
ARCHIVES OF INTERNAL MEDICINE (2002)
Impaired tuftsin activity in cirrhosis: relationship with splenic function and clinical outcome
F Trevisani et al.
GUT (2002)
Killing of Klebsiella pneumoniae by human alveolar macrophages
JM Hickman-Davis et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2002)
Leptin-deficient mice exhibit impaired host defense in gram-negative pneumonia
P Mancuso et al.
JOURNAL OF IMMUNOLOGY (2002)
Molecular pathways of monocyte emigration into the alveolar air space of intact mice
U Maus et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense
P Ye et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Gene transcription in hepatocytes during the acute phase of a systemic inflammation: from transcription factors to target genes
P Ruminy et al.
INFLAMMATION RESEARCH (2001)
Protection from respiratory virus infections can be mediated by antigen-specific CD4+ T cells that persist in the lungs
RJ Hogan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Burden of disease Implications for future research
CM Michaud et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)
Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate CD14
U Maus et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2001)
The effects of granulocyte colony-stimulating factor and neutrophil recruitment on the pulmonary chemokine response to intratracheal endotoxin
P Zhang et al.
JOURNAL OF IMMUNOLOGY (2001)
Thrombocidins, microbicidal proteins from human flood platelets, are C-terminal deletion products of CXC chemokines
J Krijgsveld et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation
JP Kress et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Chronic granulomatous disease - Report on a national registry of 368 patients
JA Winkelstein et al.
MEDICINE (2000)
Cigarette smoking and invasive pneumococcal disease.
JP Nuorti et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
The effects of chronic alcohol abuse on pulmonary glutathione homeostasis
M Moss et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)
Relation between incidence of pneumonia and protective reflexes in post-stroke patients with oral or tube feeding
K Nakajoh et al.
JOURNAL OF INTERNAL MEDICINE (2000)
gamma delta-T cells are critical for survival and early proinflammatory cytokine gene expression during murine Klebsiella pneumonia
TA Moore et al.
JOURNAL OF IMMUNOLOGY (2000)