Using of ZnCl2/AlCl3-SiO2 Catalyzed for One-Pot and Tree Substituted Synthesis of 1,4-Dihydropyridine Derivatives Via Hantzsch Reaction

In this study, we utilize ZnCl2/AlCl3-SiO2 as a moderate, retrievable, cost-effective and available catalyst at room ambient temperature and in the solvent free in order to synthesize 1,4-dihydropyridine, which entails biological characteristics in Hantzsch reaction. This reaction is as a result of compression of three components, in the solvents free and high yield products and with high-efficiency and purity.