期刊
PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS
卷 510, 期 -, 页码 208-218出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.physa.2018.06.106
关键词
Biological tissue; Elasticity; Finite element; Drosophila; Force displacement curve; Neo-Hookean
资金
- SystemsX.ch as part of the MorphogenetiX project
- Swiss National Science Foundation (SNF), Switzerland
We consider the non-linear elastic behavior of the wing disc of the Drosophila larva. In stretching experiments, this epithelial tissue shows a highly non-linear force displacement behavior. In order to understand the nature and origin of this non-linear reaction, we try to reproduce the deformation experiments using a two-dimensional finite element solution of the non-linear hyperelastic momentum balance equation. The results suggest that to a large extent the stress reaction of the tissue is due to purely geometric effects. Finally, we give a parameter estimate for a neo-Hookean constitutive model. (C) 2018 The Author(s). Published by Elsevier B.V.
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