相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Effects of Excipient Interactions on the State of the Freeze-Concentrate and Protein Stability
Sampreeti Jena et al.
PHARMACEUTICAL RESEARCH (2017)
High-concentration protein formulations: How high is high?
Patrick Garidel et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2017)
Loss of protein kinase 2 subunit alpha 2 (CK2α') effect ram sperm function after freezing and thawing process
Yuxuan He et al.
ANIMAL REPRODUCTION SCIENCE (2017)
Cold denaturation as a tool to measure protein stability
Domenico Sanfelice et al.
BIOPHYSICAL CHEMISTRY (2016)
Improved Stability of a Model IgG3 by DoE-Based Evaluation of Buffer Formulations
Brittany K. Chavez et al.
BIOMED RESEARCH INTERNATIONAL (2016)
Yeast Cyclophilins Prevent Cold Denaturation of Proteins
Mahendran Chinnamara Naicker et al.
BULLETIN OF THE KOREAN CHEMICAL SOCIETY (2016)
Design of experiments reveals critical parameters for pilot-scale freeze-and-thaw processing of L-lactic dehydrogenase
Ulrich Roessl et al.
BIOTECHNOLOGY JOURNAL (2015)
Characterisation of Stress-Induced Aggregate Size Distributions and Morphological Changes of a Bi-Specific Antibody Using Orthogonal Techniques
Zahra Hamrang et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Design of experiments reveals critical parameters for pilot-scale freeze-and-thaw processing of L-lactic dehydrogenase
Ulrich Roessl et al.
BIOTECHNOLOGY JOURNAL (2015)
Formation of protein sub-visible particles during vacuum degassing of etanercept solutions
Haibin Wang et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)
Structural Characterization of IgG1 mAb Aggregates and Particles Generated Under Various Stress Conditions
Srivalli N. Telikepalli et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Freezing-Induced Perturbation of Tertiary Structure of a Monoclonal Antibody
Lu Liu et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Visualization of Freezing Process in situ upon Cooling and Warming of Aqueous Solutions
Anatoli Bogdan et al.
SCIENTIFIC REPORTS (2014)
Frozen-state storage stability of a monoclonal antibody: Aggregation is impacted by freezing rate and solute distribution
Maria A. Miller et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Analytical approaches to assess the degradation of therapeutic proteins
Vasco Filipe et al.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2013)
Classification of protein aggregates
Linda O. Narhi et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
Protein and Solute Distribution in Drug Substance Containers During Frozen Storage and Post-Thawing: A Tool To Understand and Define Freezing-Thawing Parameters in Biotechnology Process Development
Parag Kolhe et al.
BIOTECHNOLOGY PROGRESS (2011)
Classification and Characterization of Therapeutic Antibody Aggregates
Marisa K. Joubert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Subvisible Particle Counting Provides a Sensitive Method of Detecting and Quantifying Aggregation of Monoclonal Antibody Caused by Freeze-Thawing: Insights Into the Roles of Particles in the Protein Aggregation Pathway
James G. Barnard et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2011)
The Effect of Crystallizing and Non-crystallizing Cosolutes on Succinate Buffer Crystallization and the Consequent pH Shift in Frozen Solutions
Prakash Sundaramurthi et al.
PHARMACEUTICAL RESEARCH (2011)
Frozen State Storage Instability of a Monoclonal Antibody: Aggregation as a Consequence of Trehalose Crystallization and Protein Unfolding
Satish K. Singh et al.
PHARMACEUTICAL RESEARCH (2011)
Meeting report on protein particles and immunogenicity of therapeutic proteins: Filling in the gaps in risk evaluation and mitigation
John Carpenter et al.
BIOLOGICALS (2010)
Leachables from Saline-Containing IV Bags Can Alter Therapeutic Protein Properties
Judy Y. Chang et al.
PHARMACEUTICAL RESEARCH (2010)
Mechanism of the stabilization of ribonuclease a by sorbitol: Preferential hydration is greater for the denatured than for the native protein
Guifu Xie et al.
PROTEIN SCIENCE (2010)
Quantitation of Protein Particles in Parenteral Solutions Using Micro-Flow Imaging
Chi-Ting Huang et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality
John F. Carpenter et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Thermal Analysis of Frozen Solutions: Multiple Glass Transitions in Amorphous Systems
Gregory A. Sacha et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Current perspectives on stability of protein drug products during formulation, fill and finish operations
Nitin Rathore et al.
BIOTECHNOLOGY PROGRESS (2008)
Glycation during storage and administration of monoclonal antibody formulations
Stefan Fischer et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2008)
Effects of solution conditions, processing parameters, and container materials on aggregation of a monoclonal antibody during freeze-thawing
Lisa A. Kueltzo et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Study of the individual contributions of ice formation and freeze-concentration on isothermal stability of lactate dehydrogenase during freezing
Bakul S. Bhatnagar et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
The LC/MS analysis of glycation of IgG molecules in sucrose containing formulations
Himanshu S. Gadgil et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2007)
Protein stability during freezing: Separation of stresses and mechanisms of protein stabilization
Bakul S. Bhatnagar et al.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2007)
Effects of protein aggregates: An immunologic perspective
Amy S. Rosenberg
AAPS JOURNAL (2006)
The effect of stabilizers and denaturants on the cold denaturation temperatures of proteins and implications for freeze-drying
XL Tang et al.
PHARMACEUTICAL RESEARCH (2005)
Structure-immunogenicity relationships of therapeutic proteins
S Hermeling et al.
PHARMACEUTICAL RESEARCH (2004)
Physical stability of proteins in aqueous solution: Mechanism and driving forces in nonnative protein aggregation
EY Chi et al.
PHARMACEUTICAL RESEARCH (2003)
Effect of freezing and thawing rates on denaturation of proteins in aqueous solutions
EH Cao et al.
BIOTECHNOLOGY AND BIOENGINEERING (2003)
Effect of glycine on pH changes and protein stability during freeze-thawing in phosphate buffer systems
KA Pikal-Cleland et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
Liquid fragility and the glass transition in water and aqueous solutions
CA Angell
CHEMICAL REVIEWS (2002)
Protection mechanism of Tween 80 during freeze-thawing of a model protein, LDH
A Hillgren et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2002)
Thermophysical properties of pharmaceutically compatible buffers at sub-zero temperatures: Implications for freeze-drying
EY Shalaev et al.
PHARMACEUTICAL RESEARCH (2002)
Crystal structure of a neutralizing human IgG against HIV-1: A template for vaccine design
EO Saphire et al.
SCIENCE (2001)
Calculation of hydrodynamic properties of globular proteins from their atomic-level structure
JG de la Torre et al.
BIOPHYSICAL JOURNAL (2000)