期刊
PEDIATRIC DERMATOLOGY
卷 35, 期 4, 页码 533-534出版社
WILEY
DOI: 10.1111/pde.13494
关键词
generalized lymphatic anomaly; mTOR inhibitor; sirolimus; vascular malformation
Generalized lymphatic anomaly is a rare, complex, lymphatic anomaly generally involving soft tissues, spleen, and bones. It can lead to focal skeletal fragility and pathologic effusions. A recent prospective trial of sirolimus for complicated vascular anomalies showed partial response in seven patients with generalized lymphatic anomaly treated with sirolimus with a target trough level of 10-15ng/mL for 1year (Adams etal). We describe successful treatment of generalized lymphatic anomaly with a lower-dose, long-term course of sirolimus.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据