期刊
NATURE REVIEWS IMMUNOLOGY
卷 13, 期 6, 页码 438-451出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nri3459
关键词
-
类别
资金
- US National Institutes of Health (NIH) [R01EY018836, R01EY020672, R01EY022238]
- Doris Duke Charitable Foundation, USA
- Ellison Medical Foundation, USA
- Burroughs Wellcome Fund, USA
- Reeves Foundation, USA
- Dr. E. Vernon Smith and Eloise C. Smith Endowment, USA
- Research to Prevent Blindness Unrestricted Grant, USA
- NIH [I041592, AR007279, AR0483335, GM099111, HL112303]
- Edward N. and Della L. Thome Memorial Foundation, USA
- Alexion Pharmaceuticals, USA
- National Center for Advancing Translational Sciences, USA [UL1TR000117]
Age-related macular degeneration (AMD) is a leading cause of blindness in aged individuals. Recent advances have highlighted the essential role of immune processes in the development, progression and treatment of AMD. In this Review we discuss recent discoveries related to the immunological aspects of AMD pathogenesis. We outline the diverse immune cell types, inflammatory activators and pathways that are involved. Finally, we discuss the future of inflammation-directed therapeutics to treat AMD in the growing aged population.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
